Extraosseous Ewing's sarcoma arising from the pterygomandibular space

Li, Wei; Huang, Jian; Chen, Xiao Qing; Shi, Rong; Jiang, Lei; Zhao, Yun

doi:10.4236/ojst.2011.13018

Cited by 4 publications

(2 citation statements)

References 21 publications

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“…Add 150 ml of water to 50 g of Coptidis Rhizoma, boil for 30 min, separate the liquid, add 150 ml of water to the dregs, boil for 20 min and filter to get the liquid, mix the liquid twice, concentrate to 100 ml, then put the medicinal soup into the freeze dryer equipment for lyophilisation to produce lyophilised powder, and finally combine the lyophilized powder with the film-forming material to prepare the oral film agent [11]. Open Journal of Stomatology…”

Section: Preparation Of Coptidis Rhizoma Oral Filmmentioning

confidence: 99%

Experimental Study of Emilia Sonchifolia Combined with Coptidis Rhizoma for the Prevention and Treatment of Oral Ulcer

Deng,

Wei,

Luo

et al. 2023

OJST

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Objective: This paper aims to investigate the therapeutic effect of the combination of Emilia Sonchifolia and Coptidis Rhizoma on oral ulcer rats. Methods: 36 SD rats of half male and half female were kept for 7 days, and 6 rats among them were selected as normal group by random sampling method, and the rest rats were randomly divided into model group, positive control group, Emilia Sonchifolia group, Coptidis Rhizoma group and combined group after the establishment of oral ulcer model. The normal group and model group were given blank film, the positive control group was given Guilin Watermelon Frost, and the Emilia Sonchifolia group, Coptidis Rhizoma group and combined group were given the corresponding oral film, which was administered to the ulcer for 7 days continuously, 2 times per day. The healing of oral ulcer was assessed at the end of the last day of administration, and the ulcer area was calculated on the 1st, 3rd, 5th and 7th days after successful modeling, and the serum levels of IL-2 and TNF-α in rats were detected by Emilia Sonchifolia. Results: The grading of ulcer healing in the positive control group and the combined group was better than the other groups, and the difference was statistically significant when compared with the model group (p < 0.05). On the 3rd, 5th and 7th days, the ulcer area in the Coptidis Rhizoma group, Emilia Sonchifolia group, combined group and positive control group was smaller than that in the model group, and the difference was statistically significant (p < 0.05), indicating that the Emilia Sonchifolia group, Coptidis Rhizoma group and combined group were all effective in reducing the area of oral ulcer, among which the combined group was more effective. The level of pro-inflammatory factor TNF-α was reduced and the level of anti-inflammatory factor IL-2 was increased in the Emilia Sonchifolia group,

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Section: Preparation Of Coptidis Rhizoma Oral Filmmentioning

confidence: 99%

Experimental Study of Emilia Sonchifolia Combined with Coptidis Rhizoma for the Prevention and Treatment of Oral Ulcer

Deng,

Wei,

Luo

et al. 2023

OJST

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“…[1] It arises in the soft tissues and has similar histologic, immunohistochemical, and molecular findings with Ewing's sarcoma arising intraosseously. [6] Extraosseous Ewing's sarcoma (EES) is very rare and cases have been reported from larynx, pterygomandibular space, fingers, and chest wall. We hereby report a case of a 15-year-old boy with EES arising from the maxillary sinus.…”

Section: Introductionmentioning

confidence: 99%

Extraosseous Ewing's Sarcoma of the Maxillary Sinus: A Very Rare Entity

Prakash

Reddy

Killampalli

et al. 2018

Indian Journal of Medical and Paediatric Oncology

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Ewing's sarcoma is rare sarcoma of bone and soft tissue that uncommonly involve the head and neck in both bone and soft tissue locations. The term Ewing's sarcoma family of tumors comprises both Ewing's sarcoma and peripheral neuroectodermal tumor. It was in 1975, Angervall and Enzinger described the Ewing's sarcoma arising in soft tissues (extraskeletal). The principal sites of extraskeletal Ewing's sarcoma are the paravertebral region and chest wall, generally in close association with vertebrae or the ribs. These tumors may also arise in the soft tissues of the lower extremities and rarely in the pelvic region and hip regions. Superficially located cases do occur but are rare. Here, we present a case of Ewing's sarcoma involving the maxillary sinus region. A 12-year-old boy reported to our department with a swelling on the right side of middle third of the face for 15 days. Intraorally, there was only obliteration of the labial vestibule. On histopathological examination, a provisional diagnosis of malignant round cell tumor was given. Immunohistochemistry with a panel of markers was done to come to a definitive diagnosis. CD99 positivity confirmed the diagnosis of Ewing's sarcoma.

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Sublingual Recurring Extra osseous Ewing Sarcoma: A Rare Case Report and Review of Literature

Amer

Al-aroomy

Ayad

et al. 2022

Preprint

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Background: Extera skeletal (Extraosseous) Ewing sarcoma is a rare primary tumor of the soft tissue, with an extremely high mortality rate and a bad prognosis which primarily affects young individuals. It occurs without particular clinical signs and can impact several different areas, which may delay diagnosis. Histopathological examination and immunohistochemistry are crucial for making a definite diagnosis. Besides this, early diagnosis is necessary for succeeding of the management. Case report: The objective of the present case report was to document a rare case of EES which originated from the floor of the mouth. A 37-year-old male patient came to our clinic with sublingual rapidly growing swelling. He was suffering from difficulty in opening his mouth and a feeling of dysphagia. The patient revealed during a history-taking procedure that he had undergone one surgery to remove the mass that had previously developed in the same area, knowing that he had been diagnosed in the first as a non-specific inflammatory reaction. Clinical examinations revealed a dome shape soft tissue mass. The biopsy specimen underwent histopathological and immunohistochemical analysis, which demonstrated poorly differentiated small blue round cells with positive immuno-expression of CD-99, NKX2-2, FLI-1, and Vimentin. The final diagnosis was EES based on the clinical presentation, histopathological pattern, and findings of the immunohistochemistry investigations. Radiotherapy and chemotherapy were chosen as treatment modalities for the case. Unfortunately, the patient died after three months due to the occurrence of multiple distant metastasis areas. Conclusion: Regardless of the relative rarity of Extraosseous Ewing sarcoma, it should be taken into account as a possible differential diagnosis for intraoral soft tissue masses, and accurate diagnosis with precise histopathological and immunohistochemical evaluations should be done as soon as possible. Moreover, improvement of management procedures of such cases generally provides the best chances for patient survival.

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Extraosseous Ewing's sarcoma arising from the pterygomandibular space

Cited by 4 publications

References 21 publications

Experimental Study of <i>Emilia Sonchifolia</i> Combined with <i>Coptidis Rhizoma</i> for the Prevention and Treatment of Oral Ulcer

Experimental Study of <i>Emilia Sonchifolia</i> Combined with <i>Coptidis Rhizoma</i> for the Prevention and Treatment of Oral Ulcer

Extraosseous Ewing's Sarcoma of the Maxillary Sinus: A Very Rare Entity

Sublingual Recurring Extra osseous Ewing Sarcoma: A Rare Case Report and Review of Literature

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Extraosseous Ewing's sarcoma arising from the pterygomandibular space

Cited by 4 publications

References 21 publications

Experimental Study of &lt;i&gt;Emilia Sonchifolia&lt;/i&gt; Combined with &lt;i&gt;Coptidis Rhizoma&lt;/i&gt; for the Prevention and Treatment of Oral Ulcer

Experimental Study of &lt;i&gt;Emilia Sonchifolia&lt;/i&gt; Combined with &lt;i&gt;Coptidis Rhizoma&lt;/i&gt; for the Prevention and Treatment of Oral Ulcer

Extraosseous Ewing's Sarcoma of the Maxillary Sinus: A Very Rare Entity

Sublingual Recurring Extra osseous Ewing Sarcoma: A Rare Case Report and Review of Literature

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Experimental Study of <i>Emilia Sonchifolia</i> Combined with <i>Coptidis Rhizoma</i> for the Prevention and Treatment of Oral Ulcer

Experimental Study of <i>Emilia Sonchifolia</i> Combined with <i>Coptidis Rhizoma</i> for the Prevention and Treatment of Oral Ulcer