Extravasations iatrogènes de solutés cytotoxiques ou hyperosmolaires. Prise en charge thérapeutique

Casanova, D.; Bardot, J.; Legré, R.; Magalon, G.

doi:10.1016/s1286-9325(07)48614-9

Cited by 1 publication

(19 citation statements)

References 20 publications

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“…It occurs most often during the administration of chemotherapy, or infusion of metabolic solutions [1], [4].…”

Section: Etiologiesmentioning

confidence: 99%

“…2) Antineoplastic drugs These drugs have direct cellular toxicitý (cytostatics). They can be grouped into the following three categories based on their ability to cause tissue damage upon extravasation: vesicant agents, irritant agents, and non-irritant agents (Table V) [1], [2], [4].…”

Section: ) Metabolic Solutionsmentioning

confidence: 99%

“…2) Non-vesicants and non-irritant These agents usually produce no local reaction at the injection site or to surrounding tissues upon extravasation. Occasionally, patients may notice mild inflammation and discomfort [1], [4], [13], [16].…”

Section: ) Irritantsmentioning

confidence: 99%

“…It is an iatrogenic incident that can cause skin necrosis that can extend to involve nerves, tendons, and joints leading to significant functional and aesthetic sequelae [2], [4].…”

Section: Introductionmentioning

confidence: 99%

“…Diagnostic and therapeutic management is an emergency and involves, first, informing all medical and paramedical staff of the various diagnostic aspects, the emergency procedures to be carried out, the possibilities offered by plastic surgery to overcome these incidents, and the rules to be followed to prevent them [1], [2], [4], [5].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Extravasation: Surgical Management and Prevention

Chfiri

Karti

Jalal

et al. 2022

EJMED

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Extravasation is defined as the leakage of fluid from a blood vessel into the surrounding area at the injection site. These accidents occur during injection for diagnostic or therapeutic purposes, carried out through the peripheral or central venous lines (Chemotherapy, metabolites, or contrast agent for radiographic examination). They can be the cause of skin necrosis able to progress to significant functional, cosmetic, and psychological sequelae. The saline washout technique is the emergency surgical treatment of choice for extravasations of certain products, allowing the elimination of the toxicant and the preservation of the skin. In the event of skin necrosis, covering techniques such as directed healing, grafts and flaps allow healing. The difficulty of the therapeutic management of these lesions and their unpredictable evolution, require prevention, by the development of protocols for the installation and monitoring of the venous catheters, and by the continuous training of the nursing staff to know the symptoms of extravasation, and their immediate management. The aim of this work is to present a review of the existing literature, allowing to know the diagnostic criteria, insist on the means of prevention, and propose a protocol of management.

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“…It occurs most often during the administration of chemotherapy, or infusion of metabolic solutions [1], [4].…”

Section: Etiologiesmentioning

confidence: 99%

Section: ) Metabolic Solutionsmentioning

confidence: 99%

Section: ) Irritantsmentioning

confidence: 99%

“…It is an iatrogenic incident that can cause skin necrosis that can extend to involve nerves, tendons, and joints leading to significant functional and aesthetic sequelae [2], [4].…”

Section: Introductionmentioning

confidence: 99%