We report on one of the first science observations obtained during the Calibration and Verification phase of extended ROentgen Survey with an Imaging Telescope Array (eROSITA) aboard the Spectrum-Roentgen-Gamma (SRG) mission on the famous Narrow-Line Seyfert 1 Galaxy 1H 0707-495. 1H 0707-495 is a highly variable AGN, with a complex, steep X-ray spectrum, which has been the subject of intense studies with XMM-Newton in the past. During the eROSITA observations, 1H 0707-495 showed a dramatic flux drop in about 1 day.The source is brightest at the beginning of the observations, with rapid fluctuations in count rate, followed by a subsequent decline in count rate going down close to the background level. The mean amplitude variability is a factor of 58, with a 1 error confidence interval with factors between 31 and 235. Similar, large-amplitude count-rate changes are deduced from the XMM-Newton EPIC-pn and MOS2 light curves. The energy band up to only 0.8 keV is dominating the amplitude variability, followed by a sudden drop in variability above 0.8 keV. Such extreme ultrasoft and large-amplitude flux variability in active galactic nuclei has not been detected with other X-ray observations so far. A physical explanation for the timing and spectral properties is a combination of strong relativistic effects close to the black hole and absorption by an ionized partial coverer. From the high-to the low-flux state, the partial coverer is obscuring an increasing part of the emitted X-ray radiation. Ionized outflowing absorbers are more transparent in the soft X-rays than neutral absorbers and thus show leakage effects in the soft X-rays, explaining the ultrasoft light curve.