Extremely obese children respond better than extremely obese adolescents to lifestyle interventions

Abstract

Our study demonstrated an encouraging effect of lifestyle intervention in extremely obese children ≤10 years at the end of intervention and 1 year later, but only a limited effect in extremely obese adolescents >10 years.

Молекулярно-Генетична Концепція Формування Психотипів Особистості В Дітей При Ожирінні, Асоційованому З Лактозною Інтолерантністю

“…Ожиріння в дівчат-підлітків зумовлює в 3,8 раза вищий ризик формування де-пресивних станів у зрілому жіночому віці. У дітей молодшого шкільного віку (6-10 років), які мають надлишкову вагу та ожиріння, також реєструються в 3 рази вищі показники тривожності порівняно з однолітками [4,10].…”

Pediatric Severe Obesity: Time To Establish Serious Treatments for a Serious Disease

“…3 The good news is that healthy lifestyle changes, when implemented during childhood, appear to be relatively effective in reducing adiposity, at least compared to implementation in the teenage or adult years. 4,5 This underscores the critical importance of early identification of children with severe obesity and of those who are on a trajectory toward developing the disease, because prevention is the ideal approach. Unfortunately, identification of obesity by pediatricians in primary care is less than optimal.…”

“…1 Although lifestyle modification therapy is indispensable and should be included as a component of any effective treatment approach, outcomes of studies in which this approach has been used in isolation have been poor among teens with severe obesity. 4,5 The current state of evidence suggests that more intensive interventions, potentially including pharmacotherapy and weight loss surgery, may be required to elicit meaningful reductions in adiposity and the comorbidities associated with severe obesity in this lifestyle treatment resistant adolescent population. Even if weight loss can be achieved with lifestyle modification in the short term, complex physiological adaptations occur, including changes in levels of hormones that control appetite and satiety, which continue to have strong control over feeding behaviors.…”

A Structured, Manual-Based Low-Level Intervention vs. Treatment as Usual Evaluated in a Randomized Controlled Trial for Adolescents with Extreme Obesity - the STEREO Trial

“…healthy diet/activity behaviors) [15,16]. In light of the overall weak effects of weight loss treatment on weight status in extremely obese adolescents [2,3,4], we concentrated on the participation rate as the main and sole measure of adherence, which is our primary outcome. The participation rate in an intervention aimed at promoting coping strategies and acceptance of obesity represents an appropriate type of outcome for this extreme weight group.…”

“…Based on data from systematic reviews [2,3] and clinical trials [4], adolescents with extreme obesity (BMI ≥ 99.5th percentile) cannot be expected to reach substantial weight loss through lifestyle interventions over the intermediate term. Extreme obesity entails a high risk of somatic [5] and psychiatric [6] co-morbidities.…”