2005
DOI: 10.1016/j.surneu.2004.08.044
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Extremely rare glioblastoma multiforme of the conus medullaris with holocord and brain stem metastases, leading to cranial nerve deficit and respiratory failure: a case report and review of the literature

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Cited by 38 publications
(29 citation statements)
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“…In these patients, it has a predilection to develop in the cervical spine and based on prior case reports, it has most commonly been described in the cervical, cervicothoracic [15][16][17][18], and conus medullaris [4,19,20]. Consistent with this, all five of our patients had primary spinal cord glioblastoma in the cervical or thoracic spine.…”
Section: Discussionsupporting
confidence: 84%
“…In these patients, it has a predilection to develop in the cervical spine and based on prior case reports, it has most commonly been described in the cervical, cervicothoracic [15][16][17][18], and conus medullaris [4,19,20]. Consistent with this, all five of our patients had primary spinal cord glioblastoma in the cervical or thoracic spine.…”
Section: Discussionsupporting
confidence: 84%
“…Symptomatic spinal metastases largely occur in relatively younger patients with a longer duration of survival. However, upon diagnosis of such a metastasis the prognosis is dismal, with a mean subsequent survival time of 2.8 months and poor response of the metastatic disease to radiation therapy (20)(21)(22). CSF cytology is poorly sensitive for spinal metastasis; however, GFAP expression appears to be a histological marker for potential spinal spread.…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, spinal intramedullary glioblastoma is very rare, accounting for about 1À3% of all primary intramedullary astrocytomas. 2, 13 We present here report of a patient with cervical intramedullary glioblastoma who exhibited rapid progression, together with autopsy findings. There has only been one previous report on this case.…”
Section: Introductionmentioning
confidence: 84%