2017
DOI: 10.15406/jnhfe.2017.07.00230
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Extremophilic Carbohydrate Active Enzymes (CAZymes)

Abstract: Carbohydrate active enzymes (CAZymes) are a large class of enzymes, which build and breakdown the complex carbohydrates of the cell. On the basis of their amino acid sequences they are classified in families that show conserved catalytic mechanism, structure, and active site residues, but may conflict each other in substrate specificity. The CAZymes provides a continuously updated list of the glycoside hydrolase families, GHs. This group of enzymes is classified based on functional similarity, but today they a… Show more

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Cited by 7 publications
(6 citation statements)
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“…Carbohydrate-active enzymes (CAZymes) are responsible for the biosynthesis, modification, and degradation of carbohydrates and glycoconjugates. They are involved in many metabolic pathways and are essential for microorganisms' survival [ 19 ]. By analyzing 41 Paenibacillus genomes comprising 25 species, Huang WC et al found Paebacillus genomes encode a wide repertoire of CAZymes [ 20 ].…”
Section: Resultsmentioning
confidence: 99%
“…Carbohydrate-active enzymes (CAZymes) are responsible for the biosynthesis, modification, and degradation of carbohydrates and glycoconjugates. They are involved in many metabolic pathways and are essential for microorganisms' survival [ 19 ]. By analyzing 41 Paenibacillus genomes comprising 25 species, Huang WC et al found Paebacillus genomes encode a wide repertoire of CAZymes [ 20 ].…”
Section: Resultsmentioning
confidence: 99%
“…Mass spectrometry analysis (Q-TOF LC/MS) of cultures on different cultivation media, revealed the production of a diverse set of glycosyl hydrolases-e.g., cellobiohydrolase I, β glucosidase, endoglucanase, xylanase-and auxiliary proteins. This suggests the strain as an important source of lignocellulolytic CAZymes, a large class of enzymes which build and breakdown the complex carbohydrates of the cell [355]. The activity of some of the cellulases was additionally shown on alkali treated rice straw and bagasse, which were thereby efficiently hydrolyzed into fermentable sugars.…”
Section: Secretomicsmentioning
confidence: 96%
“…Secretomics of fungal extremophilic and extremotolerant species has recently gained momentum in view of the increasing demand of new natural sources of bioactive compounds by the biotech, pharmaceutical and cosmetic industry [354,355]. Proteomics tools are therefore being increasingly applied to the identification of microbial enzymes of biotechnological value and their structural and functional characterization [356][357][358].…”
Section: Secretomicsmentioning
confidence: 99%
“…Carbohydrate-active enzymes (CAZymes) are responsible for the biosynthesis, modi cation, and degradation of carbohydrates and glycoconjugates. They are involved in many metabolic pathways and are essential for microorganism survival [19]. By analyzing 41 Paenibacillus genomes comprising 25 species, Huang WC et al found Paebacillus genomes encoded a wide repertoire of CAZymes [20].…”
Section: Identi Cation Of Carbohydrate-active Enzymesmentioning
confidence: 99%