Extremophilic Enzymes: Catalytic Features and Industrial Applications

Choudhary, Kanak; Mankar, Mangesh Kumar; Sahay, Sanjay

doi:10.1007/978-981-16-4907-3_14

Cited by 1 publication

(2 citation statements)

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“…Proteases hold about 60% shares of total enzymes sold commercially every year ( Rao et al, 1998 ; Savitha et al, 2011 ; Figure 1 ). In 2019, the worldwide protease market was 2.76 billion USD, and expected to increase over the period of 2019–2024 with the annual growth rate of 6.1% ( Choudhary et al, 2022 ). Among various proteases, alkaline proteases contribute the largest sector of the enzyme market, especially in the detergent industry ( Abidi et al, 2011 ).…”

Section: Introductionmentioning

confidence: 99%

“…Among various proteases, alkaline proteases contribute the largest sector of the enzyme market, especially in the detergent industry ( Abidi et al, 2011 ). Alkaline proteases are active at neutral to alkaline pH range and require either Asp-His-Ser triad (serine protease) or metal ions (metalloprotease) to act on the substrate ( Choudhary et al, 2022 ). Alkaline proteases are preferred over the other types of proteases because of their ability to sustain under the alkaline pH without losing the action specificity.…”

Section: Introductionmentioning

confidence: 99%

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Fungal alkaline proteases and their potential applications in different industries

Pawar

Singh

2023

Front. Microbiol.

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The consumption of various enzymes in industrial applications around the world has increased immensely. Nowadays, industries are more focused on incorporating microbial enzymes in multiple processes to avoid the hazardous effects of chemicals. Among these commercially exploited enzymes, proteases are the most abundantly used enzymes in different industries. Numerous bacterial alkaline proteases have been studied widely and are commercially available; however, fungi exhibit a broader variety of proteases than bacteria. Additionally, since fungi are often recognized as generally regarded as safe (GRAS), using them as enzyme producers is safer than using bacteria. Fungal alkaline proteases are appealing models for industrial use because of their distinct spectrum of action and enormous diversity in terms of being active under alkaline range of pH. Unlike bacteria, fungi are less studied for alkaline protease production. Moreover, group of fungi growing at alkaline pH has remained unexplored for their capability for the production of commercially valuable products that are stable at alkaline pH. The current review focuses on the detailed classification of proteases, the production of alkaline proteases from different fungi by fermentation (submerged and solid–state), and their potential applications in detergent, leather, food, pharmaceutical industries along with their important role in silk degumming, waste management and silver recovery processes. Furthermore, the promising role of alkali–tolerant and alkaliphilic fungi in enzyme production has been discussed briefly. This will highlight the need for more research on fungi growing at alkaline pH and their biotechnological potential.

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