Exudative retinal detachment following photodynamic therapy for retinal capillary hemangioma

Wong, Yuen Man; Jalil, Assad; Mathews, J P; Stanga, Paulo E

doi:10.3129/i09-258

Cited by 12 publications

(12 citation statements)

References 5 publications

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“…Aaberg et al, 2 Atebara et al, 14 Baba et al, 16 Caminal et al, 41 Cheung et al, 50 Golshevsky et al, 70 Mashayekhi et al, 118 Mennel et al, 121 Papastefanou et al, 140 Sachdeva et al, 154 Saito et al, 157 Schmidt-Erfurth et al, 166 Selver et al, 171 Stattin et al, 186 Suh et al, 191 Szabo et al, 193 Wong et al, 215 Ziemssen et al 226 …”

Section: Circumscribed Choroidal Hemangiomamentioning

confidence: 98%

“…206 Our literature search for both terms revealed four case series 2, 140, 154, 166 and 14 case reports, 14, 16, 41, 50, 70, 118, 121,157,171,186,191,193,215,226 of which 28 cases of retinal capillary hemangioma were treated with ocular PDT.…”

Section: Retinal Capillary Hemangiomamentioning

confidence: 99%

“…As for complications, there was a transient increase in subretinal fluid in seven cases (26%), 50,118,140,154,166,171,193 intravitreal hemorrhage in three eyes (7%), 16,140,186 fibrosis and macular pucker in two cases (5%) 2 and exudative retinal detachment in one case. 215 The average follow-up time of the 25 cases for which information is available was 14.2 months.…”

Section: Retinal Capillary Hemangiomamentioning

confidence: 99%

See 2 more Smart Citations

Clinical use of photodynamic therapy in ocular tumors

Çerman

Çekıç

2015

Survey of Ophthalmology

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Section: Circumscribed Choroidal Hemangiomamentioning

confidence: 98%

Section: Retinal Capillary Hemangiomamentioning

confidence: 99%

Section: Retinal Capillary Hemangiomamentioning

confidence: 99%

See 1 more Smart Citation

Clinical use of photodynamic therapy in ocular tumors

Çerman

Çekıç

2015

Survey of Ophthalmology

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“…Following treatment, patient had transient exudative RD with an area of sub-retinal hemorrhage and increase in serous detachment of the fovea at 1 week post PDT, possibly representing a reactionary edema to PDT, 6,9,12 resulting from change in tumor itself or due to breakdown of blood-retinal barrier. Despite this, there was no exaggerated cicatrical response in our case as observed by other authors.…”

Section: Discussionmentioning

confidence: 99%

“…1 Studies using verteporfin photodynamic therapy (PDT) for both juxtapapillary and peripheral RCH have mixed anatomical and functional outcomes. [2][3][4][5][6][7][8][9][10][11] Post-PDT side effects such as vascular occlusion, optic neuropathy, and tractional retinal detachment (RD) have been reported. More recently, intravitreal anti-vascular endothelial growth factor (VEGF) has been tried but the outcomes are variable.…”

Section: Introductionmentioning

confidence: 99%

Photodynamic therapy for retinal capillary hemangioma

Papastefanou

Pilli

Stinghe

et al. 2013

Eye

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Purpose To describe the results of photodynamic therapy (PDT) for juxtapapillary and peripheral retinal capillary hemangioma (RCH). Patients and methods Interventional case series of four eyes (four patients) with juxtapapillary RCH and one eye (one patient) with peripheral RCH. Two eyes with juxtapapillary RCH had received two sessions of full-fluence, double-duration PDT; whereas other two eyes had received single session of half-fluence, single-duration PDT. The peripheral RCH was treated with a single session of full-fluence, single-duration PDT. Results Two patients had von HippelLindau disease. Follow-up duration ranged from 4 months to 1 year. Pre-PDT visual acuity (VA) ranged from 20/200 to HM (juxtapapillary RCH) and 20/100 (peripheral RCH). Among the eyes with juxtapapillary RCH, tumor regression with partial resolution of macular edema was noted in two eyes (one eye each with half-fluence and full-fluence PDT), whereas two eyes had no change in tumor size with persistent macular edema. VA remained stable in three eyes and declined in one eye. In an eye with peripheral RCH, regression of tumor and macular edema with VA improvement was noted. Post-PDT complications included epiretinal membrane (one eye) and transient exudative retinal detachment (one eye). Conclusion PDT can be effective in reducing macular edema associated with RCH but this does not always correspond with an improvement in VA especially for juxtapapillary tumors.

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Persistent exudative retinal detachment after photodynamic therapy and intravitreal bevacizumab injection for multiple retinal capillary hemangiomas in a patient with von Hippel–Lindau disease

Tsai

Lau

Chen

et al. 2014

Journal of the Chinese Medical Association

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Photodynamic therapy (PDT) has been used in treating peripheral retinal capillary hemangioma (RCH) with satisfactory results. We report a rare case of von Hippel-Lindau (VHL) disease with three large peripheral RCHs, treated with PDT and intravitreal bevacizumab injection (IVB), who developed persistent bullous exudative retinal detachment (RD) despite significant tumor regression. The patient is a sporadic case of VHL disease, with a de novo nonsense mutation in codon 161 with C → T transition at nucleotide position 694 of the VHL gene. Multiple RCHs were noted in both eyes. Four small RCHs were found in the left eye and were treated with laser photocoagulation. Three large RCHs in the peripheral retina of the right eye were complicated with cystoid macular edema and subretinal fluid accumulation. The RCHs were treated with PDT combined with IVB, and bullous exudative RD developed on the second day after treatment. Three months after PDT, the tumors had regressed significantly, but exudative RD persisted, despite multiple IVB and intravitreal triamcinolone acetonide injection (IVTA). External drainage with sclera buckling, IVB, and IVTA were performed, and the retina attached after surgical intervention. The application of PDT in the treatment of RCHs and its possible complications are discussed.

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Exudative retinal detachment following photodynamic therapy for retinal capillary hemangioma

Cited by 12 publications

References 5 publications

Clinical use of photodynamic therapy in ocular tumors

Clinical use of photodynamic therapy in ocular tumors

Photodynamic therapy for retinal capillary hemangioma

Persistent exudative retinal detachment after photodynamic therapy and intravitreal bevacizumab injection for multiple retinal capillary hemangiomas in a patient with von Hippel–Lindau disease

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