“…Randomized and controlled studies have estimated that the rate of occurrence of corneal lesions among ICU patients varies widely, from 3.33% to 60% of patients admitted to this specialized sector (Korollof, Boots, Lipman, Thomas, Rickard, & Coyer, 2004;Cortese, Capp, & McKinley, 1995;Sivasankar, Jasper, Simon, Jacob, John, & Raju, 2006). A cohort study conducted in Brazil ICU patients revealed that 59.4% developed corneal injury at an A C C E P T E D M A N U S C R I P T ACCEPTED MANUSCRIPT average time of 8 or 9 days, with a predominance of punctate lesions (55.1%) and corneal ulcers (11.8%) (Werli-Alvarenga, Ercole, Botoni, Oliveira, & Chianca, 2011).…”