The purpose of this 5-year study (2002-2007) was to evaluate 90 cases of dentigerous cysts that were identified in a private dental office in terms of distribution by region (maxillary-anterior region, mandibular), age, sex, and surgical removal technique chosen. We also compared the 45 cases where PRGF was applied after cyst extirpation with the other 45 cases that were allowed to heal periosteum. We noticed that in cases where the PRGF clot was applied in the cystic geography, bone regrowth was achieved much faster.