Eyelid Eccrine Poroma: A Case Report and Review of Literature

Mencía‐Gutiérrez, Enrique; Navarro-Perea, Carmen; Gutiérrez‐Díaz, Esperanza; Cámara-Jurado, María; Bengoa-González, Álvaro

doi:10.7759/cureus.8906

Cited by 5 publications

(10 citation statements)

References 13 publications

(30 reference statements)

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“…On the eyelids, barely 11 cases of poroma have been reported [ 3 - 13 ]. The biological potential in all different histological subtypes of poromas is the same, both eccrine and apocrine [ 9 ]. Our case, the 12th, is of eccrine type as it does not have apocrine differentiation, although the apocrine subtype in poromas has never been described with eyelid involvement.…”

Section: Discussionmentioning

confidence: 99%

Eyelid Eccrine Poroma: A Case Report and Literature Review

Pérez-Trigo,

López-Ladrón-García-Borbolla,

Mencía-Gutiérrez

et al. 2024

Cureus

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Eccrine poroma is a rare benign adnexal tumor arising from intradermal cells of eccrine sweat ducts. At least two-thirds of eccrine poromas present on the extremities, most commonly on the palms and soles. They are scarcely found on the face; to date, only 11 cases of eyelid poromas have been reported in PubMed. Biopsy excision with a free margin is necessary to distinguish it from malignant lesions and avoid recurrence with possible transformation to porocarcinoma. We present the case of a 23-year-old male with a histopathological confirmation of poroma using staining with hematoxylin-eosin on the eyelid, previously clinically diagnosed with molluscum contagiosum. After four years, he has not experienced a recurrence.

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Section: Discussionmentioning

confidence: 99%

Eyelid Eccrine Poroma: A Case Report and Literature Review

Pérez-Trigo,

López-Ladrón-García-Borbolla,

Mencía-Gutiérrez

et al. 2024

Cureus

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“…According to literature, all reported poromas occurred at an older age (mostly over 60 years) [ 2 , 17 – 24 ]. Thus, we show for the first time that the tumor can also appear in early adolescence (the patient was 12–14 years old).…”

Section: Discussionmentioning

confidence: 99%

“…Occurrence of this tumor on the eyelid is rather rare [ 1 ]. Poroma usually occurs in older patients, without a gender predominance [ 2 , 3 ] and the exact pathogenesis of this lesion is unknown [ 4 ]. After radical removal, the prognosis of any form of poroma is favorable [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Pigmented Poroma of the Lower Eyelid: A Case Report and Literature Review

Bogomolets,

Rojczyk,

Hryshchenko

et al. 2023

Am J Case Rep

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Patient: Female, 30-year-old Final Diagnosis: Eccrine poroma Symptoms: Fast growing eyelid lesion Clinical Procedure: Surgical excision Specialty: Dermatology Objective: Unusual clinical course Background: Eyelid tumors belong to a diverse group of neoplasms ranging from benign lesions to malignant tumors. Poromas are common, benign, mostly unpigmented tumors of the epidermal sweat duct unit, that usually grow slowly and occur in elderly people on the palms and soles. In most poroma cases some gene fusions were detected, which were caused by chromosomal aberrations. Case Report: We report the atypical case of a 30-year-old female patient suffering for more than 15 years from a solitary, polypoid, pigmented formation with a focal tuberous surface on the left lower eyelid. The lesion was not growing during the first years, but in the last 6 months before diagnosis its size more than doubled, finally reaching 12×14 mm. It was removed and histopathological analysis confirmed the diagnosis of a rare tumor – a poroma. There were no complications during healing and no recurrence was reported. Conclusions: There have so far been only 9 reports of eyelid poromas, and the presented case significantly differed from the previous ones, as it appeared at an early age and showed rapid growth during a short time due to the war-related acute psychological stress. Moreover, it had unusual pigmentation and unpleasant smell. Reporting such untypical cases is clinically important because it is crucial to be aware of the diversity of eccrine poroma manifestation to distinguish it from malignant lesions.

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“…A poroma presents as a solitary, slowgrowing, dome-shaped, vascular-appearing papule or nodule, most commonly exhibiting on the acral surfaces of the palms or soles [3][4][5]. Clinically, the condition resembles both benign and malignant diseases, including basal cell carcinoma, squamous cell carcinoma, and pyogenic granuloma [6]. Treatment is optional, as EP is considered a benign adnexal neoplasm.…”

Section: Introductionmentioning

confidence: 99%

“…Treatment is optional, as EP is considered a benign adnexal neoplasm. However, excision is the main treatment [ 6 ]. In this article, we report a case of EP that was treated with a single session of cryotherapy and was curative.…”

Section: Introductionmentioning

confidence: 99%

Cryotherapy for Eccrine Poroma: A Case Report

Alkidaiwi¹,

Aljehani²,

Alharbi³

et al. 2023

Cureus

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Eccrine poroma (EP) is a benign adnexal tumor that is derived from acrosyringium, the intraepidermal eccrine duct of sweat glands. The standard treatment for eccrine poroma is complete excision. However, this case report highlights cryotherapy as one of the modalities in treating eccrine poroma. We present a case of a 33-year-old male patient who was a known case of generalized vitiligo since he was nine years old. During our skin checkup before starting him on phototherapy, we found a mass over the palmar aspect of the middle finger of the right hand that started to appear five years ago. The mass gradually increased in size, was painless, has no discharge, and was not associated with a history of trauma or infection. The review of systems was unremarkable. Skin examination revealed an asymptomatic, 2.0 × 1.5 cm-sized, solitary, collarette-encircled, dome-shaped, flesh-colored, non-pigmented, deep-red nodule protrusion from the palmar aspect of the middle finger of the right hand. Poroma was considered as the diagnosis, and a punch skin biopsy was performed to confirm the diagnosis and to roll out pyogenic granuloma, amelanotic melanoma, and porocarcinoma as differential diagnoses. A 3 mm punch skin biopsy was performed under local anesthesia and was found to be histologically consistent with eccrine poroma. Hence, cryosurgery was chosen based on histological favorable features. We used cryospray in a single session of 15 seconds in three applications, with five-second intervals in between (skin frosting recovery). Furthermore, the lesion was completely curative with a single session of cryotherapy. The patient followed up for one year without evidence of recurrence.

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Eyelid Eccrine Poroma: A Case Report and Review of Literature

Abstract: Mencía-Gutiérrez et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Cited by 5 publications

References 13 publications

Eyelid Eccrine Poroma: A Case Report and Literature Review

Eyelid Eccrine Poroma: A Case Report and Literature Review

Pigmented Poroma of the Lower Eyelid: A Case Report and Literature Review

Cryotherapy for Eccrine Poroma: A Case Report

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