F-18 FDG PET/CT Findings of Huge Cholesterol Granuloma in Multiple Ribs

Sohn, Myung‐Hee; Jeong, Young Jin; Jeong, Hwan-Jeong; Lim, Sungjoon; Kim, Dong Wook; Chung, Mi Sook; Yim, Chang-Yeol

doi:10.1097/rlu.0b013e31821a2778

Cited by 10 publications

(10 citation statements)

References 13 publications

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“…Both RFA and TACE m onotherapies beneficially affect survival and have been established as valuable treatment modalities for patients with unresectable HCC. Recent studies have suggested that RFA + TACE combination therapy could be expanded to patients with resectable HCC and transplant candidates [ 26 , 27 ]. According to BCLC staging and treatment algorithm, RFA is considered curative for early-stage HCC, and may be comparable to surgical resection in terms of OS and recurrence [ 26 , 28 ].…”

Section: Discussionmentioning

confidence: 99%

Combination transarterial chemoembolization and radiofrequency ablation therapy for early hepatocellular carcinoma

Song

Bae

Lee

et al. 2016

Korean J Intern Med

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Background/Aims:We compared the recurrence of hepatocellular carcinoma (HCC) and the survival of patients who received radiofrequency ablation (RFA) after transarterial chemoembolization (TACE) with patients treated with TACE or RFA alone.Methods:This study included 201 patients with HCC, who were consecutively enrolled at Seoul St. Mary’s Hospital between December 2004 and February 2010. Inclusion criteria were a single HCC ≤ 5.0 cm or up to three HCCs ≤ 3.0 cm. We used a propensity score model to compare HCC patients (n = 87) who received RFA after TACE (TACE + RFA) with those who received TACE (n = 71) or RFA alone (n = 43).Results:The median follow-up period was 33.3 months (range, 6.8 to 80.9). The TACE + RFA group showed significantly lower local recurrence than the RFA or TACE groups (hazard ratio [HR], 0.309; 95% confidence interval [CI], 0.130 to 0.736; p = 0.008; and HR, 0.352; 95% CI, 0.158 to 0.787; p = 0.011, respectively). The overall survival was significantly better in the TACE + RFA group compared to the RFA group (HR, 0.422; 95% CI, 0.185 to 0.964; p = 0.041). However, the survival benefit was not different between the TACE + RFA and TACE groups (p = 0.124). Subgroup analysis showed that among patients with a tumor size < 3 cm, the TACE + RFA group had significantly better long-term survival than those in the TACE or RFA groups (p = 0.017, p = 0.004, respectively).Conclusions:TACE + RFA combination treatment showed favorable local recurrence and better overall survival rates in early-stage HCC patients. Patients with tumors < 3 cm are likely to benefit more from TACE + RFA combination treatment. Additional studies are needed for the selection of suitable HCC patients for TACE + RFA treatment.

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Section: Discussionmentioning

confidence: 99%

Combination transarterial chemoembolization and radiofrequency ablation therapy for early hepatocellular carcinoma

Song

Bae

Lee

et al. 2016

Korean J Intern Med

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“…2 Although rare, it can affect any region of the body. [3][4][5][6] Obvious fibrosis may be the pathological basis of high 68 Ga-FAPI-04 uptake in xanthogranulomatous cholecystitis. Meanwhile, an increasing number of case studies have reported 68 Ga-FAPI-04 uptake in various nonmalignant etiologies, including myocardial infarction, 7 immunoglobulin G4-related disease, [8] tuberculosis, 9 shoulder arthritis, 10 pancreatitis, 11 and fibromas.…”

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confidence: 99%

“…Xanthogranulomatous cholecystitis is a rare variant of chronic cholecystitis characterized by lipid-laden macrophages causing xanthogranulomas, foam cells, and severe fibrosis 2 . Although rare, it can affect any region of the body 3–6 . Obvious fibrosis may be the pathological basis of high 68 Ga-FAPI-04 uptake in xanthogranulomatous cholecystitis.…”

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confidence: 99%

Xanthogranulomatous Cholecystitis Masquerading as Gallbladder Carcinoma on 68Ga-FAPI-04 PET

et al. 2022

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68Ga-FAPI-04 has great potential for the detection and staging evaluation of a variety of tumors. We report a case of suspected gallbladder carcinoma that was enrolled in a prospective study of 68Ga-FAPI-04 imaging at our institution. This case was later histopathologically confirmed as xanthogranulomatous cholecystitis. This demonstrates that xanthogranulomatous cholecystitis might be disguised as gallbladder carcinoma in 68Ga-FAPI-04 imaging. Thus, we suggest that nuclear clinicians evaluating 68Ga-FAPI-04 imaging should be aware of this possibility.

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“…Cholesterol granulomas are frequently described occurring in the temporal bone as a result of inflammatory ear disease. 1 However, they are not exclusive to this location. An intraventricular cholesterol granuloma near the septum pellucidum thought to be secondary to remote head trauma from a motor vehicle collision was previously reported.…”

Section: Discussionmentioning

confidence: 92%

Cholesterol Granuloma of Chest Wall – A very Rare Benign Tumour

Nine¹,

Haider²,

Ahmed³

et al. 2020

Cardiovasc. j.

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Cholesterol granuloma is a rare benign tumour and is described as inflammatory granulation that occurs in response to the deposition of cholesterol crystals. It is found most commonly in the paranasal sinuses or temporal bones, but there are also rare reports of their occurrence in the peritoneum, parotid gland, lymph nodes, thyroglossal duct, kidney, liver, and spleen. Involvement of the ribs has rarely been described previously. We report a case of cholesterol granuloma involving chest wall in second intercostals space of a 74-year-old male who presented with a slowly growing lesion of the anterior aspect of right side of the chest. Cardiovasc. j. 2020; 12(2): 158-161

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F-18 FDG PET/CT Findings of Huge Cholesterol Granuloma in Multiple Ribs

Cited by 10 publications

References 13 publications

Combination transarterial chemoembolization and radiofrequency ablation therapy for early hepatocellular carcinoma

Combination transarterial chemoembolization and radiofrequency ablation therapy for early hepatocellular carcinoma

Xanthogranulomatous Cholecystitis Masquerading as Gallbladder Carcinoma on 68Ga-FAPI-04 PET

Cholesterol Granuloma of Chest Wall – A very Rare Benign Tumour

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