F-18-FDG-PET/CT Leads to Diagnosis of Cryptococcal Pneumonia Where Recurrent Metastatic Rhabdomyosarcoma was Suspected

Vinson, Amy E.; Solis, Veronica; Williams, Hadyn T.; Bell, Beverly

doi:10.1097/01.rlu.0000259630.99988.d3

Cited by 10 publications

(2 citation statements)

References 5 publications

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“…Abnormal FDG uptake in lung tissue may be associated with a wide range of nonneoplastic pathological processes, including bacterial (7,8), mycobacterial (9), fungal (10,11), and viral infections (12), noninfective granulomatous diseases (13), drug reactions (14-16), and autoimmunity (17). Serial FDG-PET may be useful for the diagnosis and prediction of therapeutic response in patients with idiopathic interstitial pneumonia (18).…”

Section: Discussionmentioning

confidence: 99%

Association Between Pulmonary Uptake of Fluorodeoxyglucose Detected by Positron Emission Tomography Scanning After Radiation Therapy for Non–Small-Cell Lung Cancer and Radiation Pneumonitis

Manus

Ding

Hogg

et al. 2011

International Journal of Radiation Oncology*Biology*Physics

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Section: Discussionmentioning

confidence: 99%

Association Between Pulmonary Uptake of Fluorodeoxyglucose Detected by Positron Emission Tomography Scanning After Radiation Therapy for Non–Small-Cell Lung Cancer and Radiation Pneumonitis

Manus

Ding

Hogg

et al. 2011

International Journal of Radiation Oncology*Biology*Physics

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“…FDG-PET/CT therefore appears to be an effective tool to diagnose infection, monitor disease course and response to treatment in pneumonia. However, the overlap between FDG uptake of malignant lesions and severe infectious pneumonia may limit the use of FDG-PET as a diagnostic tool in evaluation of infectious processes [44,45]. For example, FDG-PET scans show that both bacterial pneumonia with markedly elevated FDG uptake in a patient with concomitant squamous cell carcinoma in the contralateral lung.…”

Section: Bacterial Pneumoniamentioning

confidence: 99%

Clinical Diagnosis of Bacterial Infection via FDG-PET Imaging

Wang¹,

Ning

2013

Can Chem Trans

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The key challenge in the treatment of bacterial infection is rapid identification of bacteremia at an early stage of the diseases. Currently available imaging systems such as computed tomography (CT) and magnetic resonance imaging (MRI) can only detect bacterial infection after they have become systemic or have caused significant anatomical tissue damage, and at this stage infection are challenging to treat due to the high bacterial burden. To this day positron emission tomography (PET) imaging has showed the great potential for improving the diagnosis of bacterial infection because of the high sensitivity of PET radionuclides, capability of detecting molecular biology in details (even prior to anatomic change). Fluorodeoxyglucose (FDG) PET has been developed for bacterial imaging with incredible success. Whole body PET imaging with FDG for the diagnosis of bacterial infection and monitoring response to treatment has been well established. FDG-PET will not only help to accelerate the diagnosis of infection but improve the bacterial treatment. In this review, we focus on FDG-PET imaging for diagnosing bacterial infection in the clinic.

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