Fabrication and characterization of 3D printing biocompatible crocin-loaded chitosan/collagen/hydroxyapatite-based scaffolds for bone tissue engineering applications

Jirofti, Nafiseh; Hashemi, Maryam; Moradi, Ali; Kalalinia, Fatemeh

doi:10.1016/j.ijbiomac.2023.126279

Cited by 17 publications

(2 citation statements)

References 33 publications

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“…Thus, the findings from this study suggest that the 3D-printed scaffolds loaded with Cro and composed of CS/Coll/HAP exhibit great potential as a promising option for applications in bone TE. 135 …”

Section: Chitosan-based Formulations For Tissue Engineering Applicationsmentioning

confidence: 99%

Chitosan alchemy: transforming tissue engineering and wound healing

Pramanik,

Aggarwal,

Kadi

et al. 2024

RSC Adv.

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Section: Chitosan-based Formulations For Tissue Engineering Applicationsmentioning

confidence: 99%

Chitosan alchemy: transforming tissue engineering and wound healing

Pramanik,

Aggarwal,

Kadi

et al. 2024

RSC Adv.

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“…Chitosan/collagen/nano-hydroxyapatite scaffolds prepared with the 3D printing process confirmed suitable structural properties. Loading of crocin into the scaffolds showed lower toxicity [69]. Combining an extrusion printing technique with an impregnation method, researchers created composite scaffolds from chitosan/HA/alginate.…”

Section: Preparation Techniques Of Mineralized Cs Scaffoldsmentioning

confidence: 99%

Application of Mineralized Chitosan Scaffolds in Bone Tissue Engineering

Li,

Meng,

Wang

et al. 2023

Coatings

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Chitosan (CS) is a natural cationic polysaccharide obtained via the N-deacetylation of chitin. It has various outstanding biological properties such as nontoxicity, biodegradability, biocompatibility, and antimicrobial properties. Minerals can be deposited on the CS template using different methods to construct composites with structures and functions similar to those of natural bone tissue. These ideal scaffolds can produce bone via osteogenesis, osteoinduction, and osteoconduction, with good biocompatibility and mechanical properties, and are thus considered promising novel biomaterials for repairing hard tissue defects. In the last decade, the field of mineralized CS scaffolds has provided novel fundamental knowledge and techniques to better understand the aforementioned fascinating phenomenon. This study mainly focused on the basic structures and properties of mineralized CS scaffolds to understand the current research progress and explore further development. Further, it summarizes the types, preparation methods, components, properties, and applications of mineralized CS scaffolds in bone tissue engineering during the last 5 years. The defects and shortcomings of the scaffolds are discussed, and possible improvement measures are put forward. We aimed to provide complete research progress on mineralized CS scaffolds in bone tissue engineering for researchers and clinicians, and also ideas for the next generation of mineralized CS scaffolds.

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Exploring the Potentials of Chitin and Chitosan‐Based Bioinks for 3D‐Printing of Flexible Electronics: The Future of Sustainable Bioelectronics

Kumi,

Wang,

Ejeromedoghene

et al. 2024

Small Methods

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Chitin and chitosan‐based bioink for 3D‐printed flexible electronics have tremendous potential for innovation in healthcare, agriculture, the environment, and industry. This biomaterial is suitable for 3D printing because it is highly stretchable, super‐flexible, affordable, ultrathin, and lightweight. Owing to its ease of use, on‐demand manufacturing, accurate and regulated deposition, and versatility with flexible and soft functional materials, 3D printing has revolutionized free‐form construction and end‐user customization. This study examined the potential of employing chitin and chitosan‐based bioinks to build 3D‐printed flexible electronic devices and optimize bioink formulation, printing parameters, and postprocessing processes to improve mechanical and electrical properties. The exploration of 3D‐printed chitin and chitosan‐based flexible bioelectronics will open new avenues for new flexible materials for numerous industrial applications.

show abstract

Fabrication and characterization of 3D printing biocompatible crocin-loaded chitosan/collagen/hydroxyapatite-based scaffolds for bone tissue engineering applications

Cited by 17 publications

References 33 publications

Chitosan alchemy: transforming tissue engineering and wound healing

Chitosan alchemy: transforming tissue engineering and wound healing

Application of Mineralized Chitosan Scaffolds in Bone Tissue Engineering

Exploring the Potentials of Chitin and Chitosan‐Based Bioinks for 3D‐Printing of Flexible Electronics: The Future of Sustainable Bioelectronics

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