In this work, the effect of Mo on the microstructure and properties of Ni-Mo-Al2O3 coatings by cold spraying was studied. The microstructure, composition, hardness, wear resistance and chlorine salt corrosion resistance of the coatings were analyzed by a scanning electron microscope, EDS, X-ray diffractometer, 3D profilometer, microhardness tester and friction wear tester. The results show that the coatings have low porosity and a uniform structure. The addition of Mo can improve the hardness, electrical conductivity, wear resistance and chlorine salt corrosion resistance of the coating but reduce the deposition efficiency of the powder. In general, the 80Ni-10Mo-10Al2O3 coating has the best comprehensive performance, with a hardness of 270.17 HV, friction coefficient of 0.4171 and corrosion rate of 0.287 g/m2·h in molten chloride.