Fabrication and properties of hydroxyapatite/chitosan composite scaffolds loaded with periostin for bone regeneration

Wang, Huachun; Sun, Ruixue; Huang, Shengyun; Wu, Haiwei; Zhang, Dongsheng

doi:10.1016/j.heliyon.2024.e25832

Cited by 2 publications

(1 citation statement)

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“…Over the years, different routes for obtaining of nanostructured polysaccharide@HAp systems have been developed to achieve specific properties and characteristics for different applications. In this sense, some of this research is reported here, emphasizing the synthesis and surface characteristics, such as the size and distribution of the particles, and the functional groups of the composite systems in focus: alginate@HAp, − chitosan@HAp, − and pectin@HAp …”

Section: Biomaterialsmentioning

confidence: 99%

Polysaccharide Hydroxyapatite (Nano)composites and Their Biomedical Applications: An Overview of Recent Years

Costa,

Félix Farias,

Silva-Filho

et al. 2024

ACS Omega

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Hydroxyapatite can combine with polysaccharide originating biomaterials with special applications in the biomedical field. In this review, the synthesis of (nano)composites is discussed, focusing on natural polysaccharides such as alginate, chitosan, and pectin. In this way, advances in recent years in the development of preparing materials are revised and discussed. Therefore, an overview of the recent synthesis and applications of polyssacharides@ hydroxyapatites is presented. Several studies based on chitosan@ hydroxyapatite combined with other inorganic matrices are highlighted, while pectin@hydroxyapatite is present in a smaller number of reports. Biomedical applications as drug carriers, adsorbents, and bone implants are discussed, combining their dependence with the nature of interactions on the molecular scale and the type of polysaccharides used, which is a relevant aspect to be explored.

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