Fabrication, characterization and antibacterial mechanism of in‐situ modification nano‐CaCO₃/TiO₂/CS coatings

Abstract

Calcium hydroxide reacts with carbon dioxide to produce nano‐CaCO3 and water. At the same time, the modifier sodium stearate is adsorbed on the surface of nano‐CaCO3 to form in‐situ modified nano‐CaCO3. Then, the nanoparticles are added to the CS solution. The sodium stearate on the surface of nano‐CaCO3 and the polyethylene glycol 400 on the surface of nano‐TiO2 form hydrogen bonds with the amino and hydroxyl groups of chitosan. The nanoparticles and NH3+ charges in CS coating are absorbed to the surface of cell membrane by electrostatic interaction, and result in the change of integrality and permeability of cell membrane. So, the bacteria are killed.

Antibacterial Effect of Low-Concentration ZnO Nanoparticles on Sulfate-Reducing Bacteria under Visible Light

“…When nanoparticles come into contact with bacteria, the permeability of the cell membranes increases [ 40 ]; the presence of ROS accelerates lipid damage and disrupts cell membrane integrity [ 16 ]. When the cell membrane is damaged, DNA and RNA in the cell leak into the solution [ 41 ].…”

A nanoconcrete welding strategy for constructing high-performance wound dressing

“…It is a great challenge for simultaneous strengthening and toughening in many cases. In addition, the favorable composition and surface topography of polymer-based composites can endow them with a specific anti-bacterial capability in support of tissue engineering, which can be modulated by incorporating active components and inorganic nanomaterials [ [9] , [10] , [11] ]. To construct such favorable composition and surface topography is vitally important.…”