Fabrication of a novel electrochemical sensor based on tin disulfide/multi-walled carbon nanotunbes-modified electrode for rutin determination in natural vegetation

A novel electrochemical sensor based on a molecularly imprinted polymer for highly selective and sensitive determination of rutin from herbal supplements and plant extracts

“…12 The effect of RUT on the increase in high-density lipoprotein (HDL) cholesterol and triacylglycerol levels in hyperlipidemic rats was investigated, and it was determined that RUT caused the maximum decrease in the cholesterol level. 14 When a literature review was conducted on the studies performed for RUT analysis, it was seen that the available studies are based on electrochemical nanosensors, [15][16][17][18][19][20][21][22][23][24][25][26][27] capillary electrophoresis, 28 electrochemiluminescence, 29 high-performance liquid chromatography (HPLC) with an ultraviolet (UV) detector, 8,30 HPLC with a diode array detector, 31 HPLC with chemiluminescence (CL) detection, 32 and molecularly imprinted polymer (MIP)-based electrochemical sensors. [33][34][35][36] Although the mentioned studies offer advantages such as high sensitivity for RUT determination, the most important challenges of chromatographic methods are that they require highly skilled operators, expensive equipment, and labor-intensive procedures.…”