The coronavirus disease 2019 (COVID-19) that broke out at the end of 2019 spread rapidly around the world, causing a large number of deaths and serious economic losses. Previous studies showed that aerosol transmission is one of the main pathways for the spread of COVID-19, Therefore, effective control measures are urgently needed to contain the epidemic. Nanomaterials have broad-spectrum antiviral capabilities, and their inactivation for viruses in the air has been extensively studied. This review discusses antiviral nanomaterials such as metal nanomaterials, metal oxide-based nano-photocatalysts, and nonmetallic nanomaterials; summarizes their structure and chemical properties, the efficiency of inactivating viruses, the mechanism of inactivating viruses, and the application of virus purification in the air. This review provides insights on the development and application of antiviral nanomaterials, which can help control the aerosol transmission of viruses.