Fabrication of Biopolymer-Based Piezoelectric Thin Film From Chitosan Using Solvent Casting Method

Mohammed, Nadia Syauqi Syahid; Harttar, Maziati Akmal Mat; Ahmad, Farah

doi:10.37934/araset.28.2.8089

Cited by 3 publications

(1 citation statement)

References 18 publications

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“…The use of chitosan films in composite applications has the potential to enhance the mechanical and thermal properties of the composite, making it more resilient and reliable. Therefore, understanding the mechanical and thermal properties of chitosan films is critical in developing sustainable and efficient composite materials for various industrial applications [29][30][31][32][33][34][35][36][37][38][39][40].…”

Section: Introductionmentioning

confidence: 99%

Extraction and Physicochemical Characterization of an Environmentally Friendly Biopolymer: Chitosan for Composite Matrix Application

et al. 2023

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Chitosan, which is a derivative of chitin, is particularly popular due to its biodegradable and renewable nature. However, the properties of chitosan can be inconsistent due to the extraction process and its natural origin, which poses a challenge to its use in composite materials as a matrix. The properties of chitosan can be tuned by controlling the degree of deacetylation (the extent to which acetyl groups are removed from chitin to form chitosan) and molecular weight. This paper presents a detailed study on the extraction and characterization of chitosan from shrimp shells. The structural thermal and mechanical characterization were studied using several techniques: Fourier-transform infrared spectroscopy, X-ray diffraction, thermogravimetric analysis and differential scanning calorimetry. The intrinsic viscosity and deacetylation degree were determined using various methods. The results showed an average degree of deacetylation of 77%. The chitosan films exhibited a high tensile strength of 43.9 MPa and an elongation at break of 3.14%. The thermal analysis revealed that the films had a glass transition temperature of 88 °C and a maximum thermal degradation temperature of 320 °C. The findings of this research could contribute to the development of chitosan-based materials with improved properties, leading to its wider adoption in the future for composite matrix application. The simple and efficient method used for the extraction and purification of chitosan from shrimp shells makes it a cost-effective and eco-friendly alternative to synthetic polymers.

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Section: Introductionmentioning

confidence: 99%

Extraction and Physicochemical Characterization of an Environmentally Friendly Biopolymer: Chitosan for Composite Matrix Application

et al. 2023

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Chitin and Chitosan—Foremost Hybrid Piezoelectric Materials for Energy Harvesting Applications

Banerjee,

Ali,

Naik

2024

Hybrid Materials for Piezoelectric Energy Harvesting and Conversion

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Biopolymeric Insulin Membranes for Antimicrobial, Antioxidant, and Wound Healing Applications

Aguilar-Vázquez,

Romero-Montero,

Del Prado-Audelo

et al. 2024

Pharmaceutics

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Delayed wound healing increases the wound’s vulnerability to possible infections, which may have lethal outcomes. The treatments available can be effective, but the urgency is not fully encompassed. The drug repositioning strategy proposes effective alternatives for enhancing medical therapies for chronic diseases. Likewise, applying wound dressings as biodegradable membranes is extremely attractive due to their ease of application, therapeutic effectiveness, and feasibility in industrial manufacturing. This article aims to demonstrate the pleiotropic effects during insulin repositioning in wound closure by employing a biopolymeric membrane-type formulation with insulin. We prepared biopolymeric membranes with sodium alginate cross-linked with calcium chloride, supported in a mixture of xanthan gum and guar gum, and plasticized with glycerol and sorbitol. Human insulin was combined with poloxamer 188 as a protein stabilizing agent. Our investigation encompassed physicochemical and mechanical characterization, antioxidant and biological activity through antibacterial tests, cell viability assessments, and scratch assays as an in vitro and in vivo wound model. We demonstrated that our biopolymeric insulin membranes exhibited adequate manipulation and suitable mechanical resistance, transparency, high swelling capability (1100%), and 30% antioxidant activity. Furthermore, they exhibited antibacterial activity (growth inhibition of S. aureus at 85% and P. aeruginosa at 75%, respectively), and insulin promoted wound closure in vitro with a 5.5-fold increase and 72% closure at 24 h. Also, insulin promoted in vivo wound closure with a 3.2-fold increase and 92% closure at 10 days compared with the groups without insulin, and this is the first report that demonstrates this therapeutic effect with two administrations of 0.7 IU. In conclusion, we developed a multifunctional insulin-loaded biopolymeric membrane in this study, with the main activity derived from insulin’s role in wound closure and antioxidant activity, augmented by the antimicrobial effect attributed to the polymer poloxamer 188. The synergistic combination of excipients enhances its usefulness and highlights our innovation as a promising material in wound healing materials.

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Fabrication of Biopolymer-Based Piezoelectric Thin Film From Chitosan Using Solvent Casting Method

Cited by 3 publications

References 18 publications

Extraction and Physicochemical Characterization of an Environmentally Friendly Biopolymer: Chitosan for Composite Matrix Application

Extraction and Physicochemical Characterization of an Environmentally Friendly Biopolymer: Chitosan for Composite Matrix Application

Chitin and Chitosan—Foremost Hybrid Piezoelectric Materials for Energy Harvesting Applications

Biopolymeric Insulin Membranes for Antimicrobial, Antioxidant, and Wound Healing Applications

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