Fabrication of calcium hydroxyapatite incorporated polyurethane-graphene oxide nanocomposite porous scaffolds from poly (ethylene terephthalate) waste: A green route toward bone tissue engineering

Singh, Amandeep; Banerjee, Shib Shankar; Dhiman, Vandana; Bhadada, Sanjay Kumar; Sarkar, Priyatosh; Khamrai, Moumita; Kumari, Kamlesh; Kundu, Patit Paban

doi:10.1016/j.polymer.2020.122436

Cited by 37 publications

(14 citation statements)

References 43 publications

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“…Singh et al 126 developed a nanocomposite using poly(ethylene terephthalate) waste-derived bis(2-hydroxyethyl) terephthalate, HMDI, PEG, and GO. GO acts as the nanofiller and polyol in the esterification reaction.…”

Section: Carbon Materials-based Polyurethane Compositesmentioning

confidence: 99%

“…Increasing the GO content reduced the flexibility, porosity, and pore size, but improved the antibacterial potential of the GO-PU/HAp porous scaffolds. 126 Mirmohseni et al 128 reported a PU nanohybrid comprising Cu and single layer rGO (SLrGO) by the in-situ reduction of Cu ions over graphene nanosheets. The resulting Cu/SLrGO nanohybrid was used to improve the antibacterial and antistatic properties of the WPU coating.…”

Section: Carbon Materials-based Polyurethane Compositesmentioning

confidence: 99%

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Polyurethane‐basedcomposites with promising antibacterial properties

Kasi

Sathishkumar

Zhang

et al. 2022

J of Applied Polymer Sci

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Polyurethane (PU) is a well-known synthetic polymer consisting of isocyanates, polyols, and chain extenders. The incorporation of fillers into the PU polymeric matrix, including inorganic nanomaterials, synthetic polymers, natural components, quaternary ammonium salts, and commercial drugs, bestows the endproducts with unique and improved physicochemical properties. Fillers can be used to tailor the molecular orientation, crystallinity, cross-linking, and functional chemical groups of PU-based composites. The bactericidal ability of PU composites highly depends on their surface composition, morphology, charge, and stability. Recent advancements highlight the potential of PU composites in combating bacterial infections. In this review, the cutting-edge of inorganic and organicbased PU composites for antibacterial applications is addressed. Notably, selective examples of scientific reports' key findings and their crucial information on PU composites are discussed. Furthermore, the positive impact of PU composites on the future prospects of this field is explored. This review comprehensively deliberates the values of PU composites towards practical applications in the biomedical field of antibacterial activity. This review can help researchers to gain widespread knowledge and a better understanding of PU composites for antibacterial applications.

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Section: Carbon Materials-based Polyurethane Compositesmentioning

confidence: 99%

Section: Carbon Materials-based Polyurethane Compositesmentioning

confidence: 99%

Polyurethane‐basedcomposites with promising antibacterial properties

Kasi

Sathishkumar

Zhang

et al. 2022

J of Applied Polymer Sci

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“…The usage and manufacturing of porous materials for medical purposes has experienced a considerable growth in recent years thanks to the intensive biomedical research that has been carried out. Some of the techniques that have been used until now for the production of scaffolds present some disadvantages, such as the usage of organic solvents [ 3 , 4 ]. Organic solvents can be toxic and harmful for the environment and their disposal can be rather costly.…”

Section: Introductionmentioning

confidence: 99%

Determining the Optimal Conditions for the Production by Supercritical CO2 of Biodegradable PLGA Foams for the Controlled Release of Rutin as a Medical Treatment

et al. 2021

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Poly(D,L,-lactide-co-glycolide) (PLGA) foam samples impregnated with rutin were successfully produced by supercritical foaming processes. A number of parameters such as pressure (80–200 bar), temperature (35–55 °C), depressurization rate (5–100 bar/min), ratio lactide:glycolide of the poly(D,L,-lactide-co-glycolide) (50:50 and 75:25) were studied to determine their effect on the expansion factor and on the glass transition temperature of the polymer foams and their consequences on the release profile of the rutin entrapped in them. The impregnated foams were characterized by scanning electron microscopy, differential scanning calorimetry, and mercury intrusion porosimetry. A greater impregnation of rutin into the polymer foam pores was observed as pressure was increased. The release of rutin in a phosphate buffer solution was investigated. The controlled release tests confirmed that the modification of certain variables would result in considerable differences in the drug release profiles. Thus, five-day drug release periods were achieved under high pressure and temperature while the depressurization rate remained low.

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“…Um dos artigos publicados em 2009 intitulada como "Nanohydroxyapatite/poly(ester urethane) scaffold for bone tissue engineering", relata a preparação de arcabouços compostos de nanopartículas de hidroxiapatita (nHA)/poli (éster uretano) viscoelástico biodegradável para aplicação como construtos osteocondutores para a engenharia de tecido ósseo (Boissard, Bourban, Tami, Alini, & Eglin, 2009). Em 2020, foi publicado o trabalho intitulado "Fabrication of calcium hydroxyapatite incorporated polyurethane-graphene oxide nanocomposite porous scaffolds from poly (ethylene terephthalate) waste: A green route toward bone tissue engineering", o qual aborda a preparação de arcabouços polimérico poroso e biodegradável a partir de poliuretano com a finalidade de regenerar células de osteoblastos para utilizar na restauração de tecidos ósseos danificados (Singh et al, 2020).…”

Section: Palavras-chaveunclassified

“…Os PU´s do tipo arcabouço são bastante utilizados na engenharia de tecidos, na forma de nanocompósitos, a partir da incorporação de hidroxiapatita de cálcio na sua matriz polimérica que lhe confere propriedades bioativas e regeneração do tecido ósseo (Singh et al, 2020). Na síntese de nanocompósitos, nanomateriais são incorporadas em uma matriz, seja ela polimérica, cerâmica ou metálica, para melhorar suas propriedades, sendo elas, resistência, dureza, estabilidade térmica e leveza, os nanomateriais incorporados podem ser nanopartículas orgânicas, inorgânicas e poliméricas (hidroxiapatita, argila, grafeno e nanopartículas metálicas) (Akhan, Oktay, Özdemir, Madakbaş, & Apohan, 2020;Asadi et al, 2017).…”

Section: Introductionunclassified

Monitoramento de artigos sobre a utilização de nanocompósitos com matriz de poliuretano aplicados à engenharia de tecidos para o reparo ósseo

Silva

Trindade

Filho

et al. 2021

RSD

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Nanocompósitos com matriz de poliuretano são materiais com propriedades interessantes para a Engenharia de tecidos, podendo ser usados na fabricação de arcabouço para regeneração óssea. O objetivo dessa pesquisa foi avaliar a evolução das publicações cientificas relacionadas a nanocompósitos com matriz de poliuretano aplicados à regeneração do tecido ósseo. Realizou-se buscas nas bases de periódicos Web of Science e Scopus, fazendo uso de uma combinação de palavras-chave, e os resultados reportados foram tabulados e analisados. Verificou-se que os primeiros documentos datam de 2009. A China detém o maior número de publicações, seguido pela Malásia e Vietnã. As principais áreas de pesquisa são Engenharia, Ciência dos materiais e Engenharia química. Percebeu-se uma valorização crescente da temática, com aumento na produção e impacto dessas publicações. Pode-se considerar que a questão levantada possui grande relevância por ser um campo de estudos promissor que promete trazer importantes avanços à engenharia de tecidos ósseos.

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Fabrication of calcium hydroxyapatite incorporated polyurethane-graphene oxide nanocomposite porous scaffolds from poly (ethylene terephthalate) waste: A green route toward bone tissue engineering

Cited by 37 publications

References 43 publications

Polyurethane‐basedcomposites with promising antibacterial properties

Polyurethane‐basedcomposites with promising antibacterial properties

Determining the Optimal Conditions for the Production by Supercritical CO2 of Biodegradable PLGA Foams for the Controlled Release of Rutin as a Medical Treatment

Monitoramento de artigos sobre a utilização de nanocompósitos com matriz de poliuretano aplicados à engenharia de tecidos para o reparo ósseo

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