Fabrication of cellulose-based scaffold with microarchitecture using a leaching technique for biomedical applications

Shin, Eun Joo; Choi, Soon Mo; Singh, Deepti; Zo, Sun Mi; Lee, Yang Hun; Kim, Joon Ho; Han, Sung Soo

doi:10.1007/s10570-014-0368-2

Cited by 37 publications

(10 citation statements)

References 33 publications

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“…Aerogel with advanced properties and a three dimensional crosslinked network structure has attracted great interests from researchers because of its high surface area, low density, and exceptional thermal insulation capability . Cellulose‐based aerogels have been recently reported due to their flexibility, advanced strength, biocompatibility, and biodegradability . Common aerogels like silica‐based ones are usually manufactured by sol–gel method.…”

Section: Introductionmentioning

confidence: 99%

Super absorbent, light, and highly flame retardant cellulose‐based aerogel crosslinked with citric acid

Kaya

2017

J of Applied Polymer Sci

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Light (0.089-0.12 g cm 23 ), superabsorbent (84-99 g water/1 g aerogel), and highly flame retardant non-crosslinked cellulose aerogel (CA) and crosslinked cellulose aerogel (CL-CA) have been successfully produced from pruning waste of blueberry tree. The prepared aerogels with three dimensional porous structure have a remarkably thermal stability and flame retardant performance, which totally burned after 136-200 s. Besides, CA and CL-CA have an important Brunauer-Emmet-Teller surface area, which are 348 and 275 m 2 g 21 , respectively. The concepts of this study are simple and bio-wastes are easily available and sustainable at low cost, and therefore, the current process is appropriate for industrial scale production and has a significant potential in the future of green materials.

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Section: Introductionmentioning

confidence: 99%

Super absorbent, light, and highly flame retardant cellulose‐based aerogel crosslinked with citric acid

Kaya

2017

J of Applied Polymer Sci

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“…After the IL removal, the biocompatibility of the prepared matrices and copolymers were confirmed, which showed no or negligible in vitro cytotoxicity. 48,103,107,112,166,188,261,262 For instance, no apparent inhibition effect of 3T3 fibroblast was observed when the concentration of cellulose-g-PLA copolymer was below 700mg/L. 147 ILs did not cause any deleterious effect on cell viability, which in turn suggests efficient IL removal from the chitin structures.…”

Section: Green Chemistrymentioning

confidence: 97%

Ionic liquids for the preparation of biopolymer materials for drug/gene delivery: a review

et al. 2018

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“…Ionic liquids have recently found their way into nanofibers intended for biomedical applications. In 2014, AMIMCl was used as a solvent in the fabrication of a cellulose-based tissue engineering scaffold with a tunable microarchitecture [176]. These scaffolds were tested by culturing fibroblast cells on them for 15 days to compare the biocompatibility of the samples to a control 2D cell culture dish.…”

Section: Tissue Regenerationmentioning

confidence: 99%

Protein and Polysaccharide-Based Fiber Materials Generated from Ionic Liquids: A Review

et al. 2020

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Natural biomacromolecules such as structural proteins and polysaccharides are composed of the basic building blocks of life: amino acids and carbohydrates. Understanding their molecular structure, self-assembly and interaction in solvents such as ionic liquids (ILs) is critical for unleashing a flora of new materials, revolutionizing the way we fabricate multi-structural and multi-functional systems with tunable physicochemical properties. Ionic liquids are superior to organic solvents because they do not produce unwanted by-products and are considered green substitutes because of their reusability. In addition, they will significantly improve the miscibility of biopolymers with other materials while maintaining the mechanical properties of the biopolymer in the final product. Understanding and controlling the physicochemical properties of biopolymers in ionic liquids matrices will be crucial for progress leading to the ability to fabricate robust multi-level structural 1D fiber materials. It will also help to predict the relationship between fiber conformation and protein secondary structures or carbohydrate crystallinity, thus creating potential applications for cell growth signaling, ionic conductivity, liquid diffusion and thermal conductivity, and several applications in biomedicine and environmental science. This will also enable the regeneration of biopolymer composite fiber materials with useful functionalities and customizable options critical for additive manufacturing. The specific capabilities of these fiber materials have been shown to vary based on their fabrication methods including electrospinning and post-treatments. This review serves to provide basic knowledge of these commonly utilized protein and polysaccharide biopolymers and their fiber fabrication methods from various ionic liquids, as well as the effect of post-treatments on these fiber materials and their applications in biomedical and pharmaceutical research, wound healing, environmental filters and sustainable and green chemistry research.

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Fabrication of cellulose-based scaffold with microarchitecture using a leaching technique for biomedical applications

Cited by 37 publications

References 33 publications

Super absorbent, light, and highly flame retardant cellulose‐based aerogel crosslinked with citric acid

Super absorbent, light, and highly flame retardant cellulose‐based aerogel crosslinked with citric acid

Ionic liquids for the preparation of biopolymer materials for drug/gene delivery: a review

Protein and Polysaccharide-Based Fiber Materials Generated from Ionic Liquids: A Review

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