Fabrication of ciprofloxacin loaded alginate/cockle shell powder nanobiocomposite bone scaffold
Huai Li Wong,
Jacinta Santhanam,
Shiow Fern Ng
et al.
Abstract:Orthopedic implant infection is one of the most challenging issues in bone tissue engineering industry. Hence, local delivery of antibiotics incorporated into a fabricated bone scaffold possibly provides a more rapid bacteria inhibitory effect. In this study, pure ciprofloxacin loaded alginate/cockle shell powder nanobiocomposite bone scaffolds are fabricated with 5 wt% and 10 wt% ciprofloxacin respectively and tested for drug encapsulation, drug release and antibacterial properties towards common implant infe… Show more
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