Thiram, as one widely used dithiocarbamate pesticide, has been considered seriously detrimental to food safety and human health because of poor efficiency, nonstandard/superfluous usage, and lack of a targeting effect. Developing highperformance sensors for thirams is strongly needed. With the rapid development of chemistry, biology, and materials science, many sensors have been constructed for thiram with high sensitivity and selectivity. Regarding the energy form of the signal, recognition mode, and detection principle, recent advances in the design and construction of optical and electrochemical sensors for thiram are summarized in this review, including colorimetric, luminescent, chemiluminescent, and electrochemical sensors. The advantages and disadvantages of the sensors for thiram including sensitivity, ability to avoid interference, recognition mechanism, signal output mode, and practicability are clarified in detail. Furthermore, the challenges faced, effective restrictions, and next direction of development are proposed for achieving more sensitive and selective analysis of thiram with less interference. We desire that this review will supply a solid theoretical basis and inspiration to generate innovative thinking for achieving new progress on thiram assays and the commercialization of the developed sensors in the future.