Fabrication of electrospun gum Arabic–polyvinyl alcohol blend nanofibers for improved viability of the probiotic

Fareed, Faisal; Saeed, Farhan; Afzaal, Muhammad; Imran, Ali; Hussain, Muzzamal; Mahmood, Kaiser; Shah, Yasir Abbas; Hussain, Muzamal; Ateeq, Huda

doi:10.1007/s13197-022-05567-1

Cited by 25 publications

(10 citation statements)

References 42 publications

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“…XRD is one of the most influential and valuable technologies in determining the structural properties of materials (Fareed et al ., 2022). Figure 5 shows XRD patterns of the PUL, NaCAS powders, and PUL/NaCAS nanofibres at different concentrations.…”

Section: Resultsmentioning

confidence: 99%

Replacing pullulan with sodium caseinate to enhance the properties of pullulan nanofibres

Dabora,

Jiang,

Mahdi

et al. 2024

Int J of Food Sci Tech

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SummaryThis study investigated the feasibility of using sodium caseinate (NaCAS) to improve the properties of electrospun pullulan (PUL) nanofibres. Replacing PUL with 50% NaCAS [50:50(PUL: NaCAS)] resulted in appropriate viscosity for fibre formation (968.93 mPa.s), increased solution conductivity (1682.50 μS cm−1), decreased surface tension (59.55 mN m−1), which led to forming beadles' fibres with the smallest diameter (141.21 nm), highest water contact angles (117°), and highest thermal stability (24.03% residue weight at 600 °C). X‐ray diffraction and Fourier‐transform infrared spectroscopy analyses provided insights into nanofibres' structural and chemical properties and indicated successful blending of the PUL and NaCAS. Results indicated that replacing PUL with 50% NaCAS improved fibre properties. These findings contribute to the development of novel biopolymer‐based nanofibres with potential applications in various industries, including food and bioencapsulation.

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Section: Resultsmentioning

confidence: 99%

Replacing pullulan with sodium caseinate to enhance the properties of pullulan nanofibres

Dabora,

Jiang,

Mahdi

et al. 2024

Int J of Food Sci Tech

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“…This study further demonstrated that sensitive OLE can be encapsulated and used to design functional food and nanodelivery of pharmaceuticals. In the study of Fareed et al [110], Lactobacillus acidophilus, a probiotic, was encapsulated in blended nanofibers of GA and polyvinyl alcohol using an electrospinning technique. The results showed that probiotic-encapsulated nanofibers had high average size, zeta potential, moisture contents, thickness, tensile strength, and elongation at break compared to the free probiotics.…”

Section: Encapsulation Methodsmentioning

confidence: 99%

“…The results showed that probiotic-encapsulated nanofibers had high average size, zeta potential, moisture contents, thickness, tensile strength, and elongation at break compared to the free probiotics. In vitro assay showed that encapsulated probiotics had a significantly high viability rate compared to free cells, which lost their viability under simulated gastrointestinal conditions [110]. The addition of starch/water soluble yellow mustard mucilage to electrosprayed nanocapsules loaded with thymol and carvacrol improved EE (84.10%), surface morphology, and release kinetics [111].…”

Section: Encapsulation Methodsmentioning

confidence: 99%

Encapsulation of Hydrophobic Bioactive Substances for Food Applications: Carriers, Techniques, and Biosafety

Shavronskaya,

Noskova,

Skvortsova

et al. 2023

Journal of Food Processing and Preservation

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Biologically active substances (BASs) are used as novel ingredients to design functional foods. These functional foods are alternate approaches to treat or cure chronic diseases. However, the application of BASs is limited due to their hydrophobic nature, low bioavailability, sensitivity to gastric acid, and environmental conditions (i.e., high temperatures, radiation, pH, and oxygen). Thus, research has been channeled to find ways of curbing these limitations. This review provides an overview of the modern methods for BAS encapsulation, carrier classifications, benefits, and drawbacks as well as the biosafety of encapsulated BASs. Encapsulation of BASs into organic/inorganic carriers or composites overcomes the limitations mentioned above. In addition, encapsulation enables the controlled release of active compounds to target cells. The market for encapsulated foods has grown globally at a significant pace due to their various applications as functional foods, dietary supplements, and other products. It is estimated that by 2027, the market worth of encapsulated foods will be valued at $17 billion.

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“…Fareed et al investigated the gut fate of probiotic-loaded nanofibers. Specifically, Lactobacillus acidophilus strains were loaded in a mixture of Arabic gum and PVA and were electrospun into nanofibers [ 45 ]. The fibrous system displayed a good encapsulation capability, improving the tolerance to simulated gastric juice (SGJ) and successfully protecting the microorganisms against a harsh environment.…”

Section: Biofabrication Approachesmentioning

confidence: 99%

Emerging Multiscale Biofabrication Approaches for Bacteriotherapy

Rovelli,

Cecchini,

Zavagna

et al. 2024

Molecules

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Bacteriotherapy is emerging as a strategic and effective approach to treat infections by providing putatively harmless bacteria (i.e., probiotics) as antagonists to pathogens. Proper delivery of probiotics or their metabolites (i.e., post-biotics) can facilitate their availing of biomaterial encapsulation via innovative manufacturing technologies. This review paper aims to provide the most recent biomaterial-assisted strategies proposed to treat infections or dysbiosis using bacteriotherapy. We revised the encapsulation processes across multiscale biomaterial approaches, which could be ideal for targeting different tissues and suit diverse therapeutic opportunities. Hydrogels, and specifically polysaccharides, are the focus of this review, as they have been reported to better sustain the vitality of the live cells incorporated. Specifically, the approaches used for fabricating hydrogel-based devices with increasing dimensionality (D)—namely, 0D (i.e., particles), 1D (i.e., fibers), 2D (i.e., fiber meshes), and 3D (i.e., scaffolds)—endowed with probiotics, were detailed by describing their advantages and challenges, along with a future overlook in the field. Electrospinning, electrospray, and 3D bioprinting were investigated as new biofabrication methods for probiotic encapsulation within multidimensional matrices. Finally, examples of biomaterial-based systems for cell and possibly post-biotic release were reported.

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Fabrication of electrospun gum Arabic–polyvinyl alcohol blend nanofibers for improved viability of the probiotic

Cited by 25 publications

References 42 publications

Replacing pullulan with sodium caseinate to enhance the properties of pullulan nanofibres

Replacing pullulan with sodium caseinate to enhance the properties of pullulan nanofibres

Encapsulation of Hydrophobic Bioactive Substances for Food Applications: Carriers, Techniques, and Biosafety

Emerging Multiscale Biofabrication Approaches for Bacteriotherapy

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