Fabrication of fluidic-based memristor sensor for dengue virus detection

Hadis, Nor Shahanim Mohamad; Manaf, Asrulnizam Abd; Ngalim, Siti Hawa; Herman, Sukreen Hana; Sawada, Kazuaki; Fauzi, Normasni Ad

doi:10.1109/primeasia.2017.8280375

Cited by 7 publications

(3 citation statements)

References 9 publications

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“…13 To address this challenge, complex surface patterning 14 or nanowire 15 designs are necessary. While most memristive sensors so far have focused on the detection of complex biomolecules such as DNA aptamers, 16 cancer markers 17 or the ebola and dengue virus, 18,19 sensing of easier biomolecules such as glucose was demonstrated but with a lack in both sensitivity (10-40 mM) and selectivity. 20 Organic memristive devices have been designed with several different voltage thresholds or volatile switching mechanisms.…”

Section: Introductionmentioning

confidence: 99%

Photomemristive sensing via charge storage in 2D carbon nitrides

et al. 2022

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Section: Introductionmentioning

confidence: 99%

Photomemristive sensing via charge storage in 2D carbon nitrides

et al. 2022

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“…It is observed that for all diameter size, the detection can be achieved the for the maximum concentration 416 nM down to 52 nM [ 27 ]. However, at low concentration, the sensing capabilities (resistance ratio) is not clearly observed as compared to higher diameter sensing area.…”

Section: Resultsmentioning

confidence: 99%

Fabrication and Characterization of Simple Structure Fluidic-Based Memristor for Immunosensing of NS1 Protein Application

et al. 2020

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Non-structural protein 1 (NS1 protein) is becoming a commonplace biomarker for the diagnostic of early detection of dengue. In this study, we sought to use a label-free approach of detecting NS1 protein by harnessing fluidic-based memristor sensor. The sensor was fabricated using sol-gel spin coating technique, by which TiO2 thin film is coated on the surface of Indium tin oxide (ITO) and a glass substrate. The sensor was then functionalized with glycidoxypropyl-trimethoxysilane (GPTS), acting as antibody for NS1. The addition of the target NS1 formed an antibody-antigen complex which altered the physical and electrical properties in sensing region. Sensing of the sensor is incumbent upon the measurement of Off-On resistance ratio. Imaging with Field Emission Scanning Electron Microscope (FESEM) evinced the successful immobilization of the antibody and the subsequent capture of the NS1 protein by the immobilized antibody. The detection limit actualized by the developed sensor was 52 nM and the diameter of 2 mm gives the most optimal measurement. The developed sensor demonstrated an immense potential towards the development of label-free diagnostic of early dengue infection.

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“…The results showed a sensitivity of 6.53 × 10 -3 nM -1 and limit of detection of 5.02 nm/nM based on fluidic-based characteristics. The output results are based on the change in electrical conductivity due to specific binding between the dengue virus antibody and NS1 glycoprotein of DENV (Hadis et al, 2017). The label-free DENV identification method has been developed by functionalized tampered optical fiber sensor and complimentary recombinant antibodies.…”

Section: Future Perspectives and Electrical Biosensors Technologiesmentioning

confidence: 99%

Dengue virus infection: A review of advances in the emerging rapid detection methods

Hussain¹,

Ali²,

Liu³

et al. 2022

Biocell

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Dengue virus infections are increasing worldwide generally and in Asia, Central and South America and Africa, particularly. It poses a serious threat to the children population. The rapid and accurate diagnostic systems are essentially required due to lack of effective vaccine against dengue virus and the progressive spread of the dengue virus infection. The recent progress in developing micro-and nano-fabrication techniques has led to low cost and scale down the biomedical point-of-care devices. Starting from the conventional and modern available methods for the diagnosis of dengue infection, this review examines several emerging rapid and point-of-care diagnostic devices that hold significant potential for the progress in smart diagnosis tools. The given review revealed that an effective vaccine is required urgently against all the dengue virus serotypes. However, the rapid detection methods of dengue virus help in early treatment and significantly reduce the dengue virus outbreak.

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Fabrication of fluidic-based memristor sensor for dengue virus detection

Cited by 7 publications

References 9 publications

Photomemristive sensing via charge storage in 2D carbon nitrides

Photomemristive sensing via charge storage in 2D carbon nitrides

Fabrication and Characterization of Simple Structure Fluidic-Based Memristor for Immunosensing of NS1 Protein Application

Dengue virus infection: A review of advances in the emerging rapid detection methods

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