Fabrication of novel electrochemical sensors based on modification with different polymorphs of MnO<sub>2</sub>nanoparticles. Application to furosemide analysis in pharmaceutical and urine samples

Said, Mohamed I.; Rageh, Azza H.; Abdel‐aal, Fatma A. M.

doi:10.1039/c8ra02978d

Cited by 35 publications

(8 citation statements)

References 66 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For the Fe-promoted systems, the far-infrared region becomes much less structured, as the presence of Fe species seems to bring about more disorder in the crystallographic structure of MnO 2 . FIR spectra of Fe-doped MnO 2 (bluish lines in Figure 2b) suggest the presence of different polymorphs with respect to the previous samples, as already found by XRD analysis [62]; one peak is evident, whereas RAM-MnO 2 definitely causes the appearance of the well-defined band at about 360 cm −1 [60]. As far as it concerns the morphological feature of the examined samples, FEG-SEM microscopy has been carried out in order to visualize the nanoparticles surface texture.…”

Section: Nanoelectrocatalysts Physicochemical Featuressupporting

confidence: 74%

ORR in Non-Aqueous Solvent for Li-Air Batteries: The Influence of Doped MnO2-Nanoelectrocatalyst

et al. 2020

View full text Add to dashboard Cite

One of the major drawbacks in Lithium-air batteries is the sluggish kinetics of the oxygen reduction reaction (ORR). In this context, better performances can be achieved by adopting a suitable electrocatalyst, such as MnO2. Herein, we tried to design nano-MnO2 tuning the final ORR electroactivity by tailoring the doping agent (Co or Fe) and its content (2% or 5% molar ratios). Staircase-linear sweep voltammetries (S-LSV) were performed to investigate the nanopowders electrocatalytic behavior in organic solvent (propylene carbonate, PC and 0.15 M LiNO3 as electrolyte). Two percent Co-doped MnO2 revealed to be the best-performing sample in terms of ORR onset shift (of ~130 mV with respect to bare glassy carbon electrode), due to its great lattice defectivity and presence of the highly electroactive γ polymorph (by X-ray diffraction analyses, XRPD and infrared spectroscopy, FTIR). 5% Co together with 2% Fe could also be promising, since they exhibited fewer diffusive limitations, mainly due to their peculiar pore distribution (by Brunauer–Emmett-Teller, BET) that disfavored the cathode clogging. Particularly, a too-high Fe content led to iron segregation (by energy dispersive X-ray spectroscopy, EDX, X-ray photoelectron spectroscopy, XPS and FTIR) provoking a decrease of the electroactive sites, with negative consequences for the ORR.

show abstract

Section: Nanoelectrocatalysts Physicochemical Featuressupporting

confidence: 74%

ORR in Non-Aqueous Solvent for Li-Air Batteries: The Influence of Doped MnO2-Nanoelectrocatalyst

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Furosemide is the most common drug detected in athlete samples and its occurrence has increased over the years . Only a few studies on the electrochemical determination of furosemide have been reported, where most of them are lacking a quantification range ,− and are using complex electrode modifications. , This motivated us to study this diuretic drug on the proposed μ-ES. The sensitive detection of furosemide was performed using the SWV technique in 0.1 M phosphate buffer of pH 2.2.…”

Section: Resultsmentioning

confidence: 99%

Carbon Nanotube Microelectrode Set: Detection of Biomolecules to Heavy Metals

et al. 2021

View full text Add to dashboard Cite

An ultrasensitive electrochemical microelectrode set (μ-ES), where all three electrodes are made of highly densified carbon nanotube fiber (HD-CNTf) cross sections (length ∼40 μm), embedded in an inert polymer matrix, and exposed open-ended CNTs at the interface, is presented here. Bare open ends of HD-CNTf rods were used as the working (∼40 μm diameter) and counter (∼94 μm diameter) electrodes, while the cross section of a ∼94 μm diameter was electroplated with Ag/AgCl and coated with Nafion to employ as a quasi-reference electrode. The Ag/AgCl/Nafion-coated HD-CNTf rod quasi-reference electrode provided a very stable potential comparable to the commercial porous-junction Ag/AgCl reference electrode. The HD-CNTf rod μ-ES has been evaluated by electrochemical determination of biologically important analytes, i.e., dopamine (DA), β-nicotinamide adenine dinucleotide (NADH), a diuretic drug, i.e., furosemide, and a heavy metal, i.e., lead ions (Pb2+). Different voltammetric techniques were employed during the study, i.e., cyclic voltammetry (CV), square wave voltammetry (SWV), amperometry, and square wave anodic stripping voltammetry (SWASV). The direct metallic connection to CNTs gives access to the exceptional properties of highly ordered open-ended CNTs as electrochemical sensors. The distinct structural and electronic properties of aligned HD-CNTf rods in the μ-ES demonstrate fast electron transfer kinetics and offer excellent detection performance during testing for different analytes with wide linear ranges, excellent sensitivity, and very low limits of detection.

show abstract

“…Here, the separation of the peaks for the cathodic and anodic peaks for the two types of MnO 2 /chitosan-modified PGE was only slightly higher than the theoretical value (∆E p = 0.059) signifying the redox couple reversibility of these electrodes, while others demonstrate quasi-reversible behavior at higher values of ∆E p . The chitosan acts to bind the MnO 2 NPs on the electrode surface leading to an increase in peak current because of the electrocatalytic synergy between them [97]. World Journal of Nano Science and Engineering Also, Yang et al gave the CV plot of GPNs/GCE using 5 mM [Fe(CN) 6] +4 in PBS with 0.1 mol/L KCl.…”

Section: Logmentioning

confidence: 99%

Nanoparticles Modified Electrodes: Synthesis, Modification, and Characterization—A Review

Falola¹

2022

WJNSE

View full text Add to dashboard Cite

Nanoparticles offer unique features such as a larger surface area and enhanced electrochemical performance compared to their contemporary matters. These properties make them suitable to be considered in bridging the lacunae associated with the use of bare electrodes in electrochemical sensors. Nanomaterials enhance the redox reversibility on the electrodes' surfaces, hence, improving the reproducibility, sensitivity, and limit of detection of the electrodes/sensors. Their methods of synthesis (top-to-bottom and bottom-to-to-top) are tailored toward manipulating their sizes, shapes, and preventing their agglomeration. This review paper provides a synopsis on research done in synthesizing nanoparticles, modifying electrodes, and pinpointing the improved performances of the modified electrodes via known characteristic techniques, namely: cyclic voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy. In addition, a perspective is given in terms of increasing the lifespan of the working electrodes and the need for non-faradaic sensors.

show abstract

Fabrication of novel electrochemical sensors based on modification with different polymorphs of MnO₂nanoparticles. Application to furosemide analysis in pharmaceutical and urine samples

Abstract: A novel MnO2 nanoparticles/chitosan-modified pencil graphite electrode (MnO2 NPs/CS/PGE) was constructed using two different MnO2 polymorphs (γ-MnO2 and ε-MnO2 nanoparticles).

Cited by 35 publications

References 66 publications

ORR in Non-Aqueous Solvent for Li-Air Batteries: The Influence of Doped MnO2-Nanoelectrocatalyst

ORR in Non-Aqueous Solvent for Li-Air Batteries: The Influence of Doped MnO2-Nanoelectrocatalyst

Carbon Nanotube Microelectrode Set: Detection of Biomolecules to Heavy Metals

Nanoparticles Modified Electrodes: Synthesis, Modification, and Characterization—A Review

Contact Info

Product

Resources

About

Fabrication of novel electrochemical sensors based on modification with different polymorphs of MnO2nanoparticles. Application to furosemide analysis in pharmaceutical and urine samples

Abstract: A novel MnO2 nanoparticles/chitosan-modified pencil graphite electrode (MnO2 NPs/CS/PGE) was constructed using two different MnO2 polymorphs (γ-MnO2 and ε-MnO2 nanoparticles).

Cited by 35 publications

References 66 publications

ORR in Non-Aqueous Solvent for Li-Air Batteries: The Influence of Doped MnO2-Nanoelectrocatalyst

ORR in Non-Aqueous Solvent for Li-Air Batteries: The Influence of Doped MnO2-Nanoelectrocatalyst

Carbon Nanotube Microelectrode Set: Detection of Biomolecules to Heavy Metals

Nanoparticles Modified Electrodes: Synthesis, Modification, and Characterization—A Review

Contact Info

Product

Resources

About

Fabrication of novel electrochemical sensors based on modification with different polymorphs of MnO₂nanoparticles. Application to furosemide analysis in pharmaceutical and urine samples