Fabrication of peppermint essential oil nanoemulsions by spontaneous method: Effect of preparing conditions on droplet size

Barakat, Hassan; Mehrnia, Mohammad Amin; Nasehi, Behzad; Alipour, Mohammad Amin

doi:10.1002/ffj.3455

Cited by 29 publications

(17 citation statements)

References 18 publications

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“…Alcohol-free perfumes based on micro- and nanoemulsions are already present in the patent literature [19,20,21,22], however, apart from additional solubilizers, such as polyols or paraffin hydrocarbons, the compositions of the perfumes in the above-mentioned patents have cationic or anionic surfactants, which can be an irritant to the skin. Nanoemulsions that serve as a matrix for fragrance substances used in cosmetics are also described in the literature [18,23,24,25,26,27,28] these are primarily solutions for emulsification of a single lipophilic component that forms the oil phase of a nanoemulsion (e.g., D-limonene) [18,23,24]. On the other hand, the fragrance compositions contain up to twenty compounds with various chemical structures (alcohols, phenols, aldehydes, esters, saturated, unsaturated, cyclic, and branched hydrocarbons), and as a result they are a difficult base for obtaining stable nanoemulsion systems.…”

Section: Introductionmentioning

confidence: 99%

Preparation and Characterization of Water-Based Nano-Perfumes

et al. 2018

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The application of nanoemulsions as a novel delivery system for lipophilic materials, such as essential oils, flavors, and fragrances is one of the growing technologies used in cosmetic, pharmaceutical, and food industries. Their characteristic properties, like small droplet size with high interfacial area, transparent or semi-transparent appearance, low viscosity, and high kinetic stability, make them a perfect vehicle for fragrances, in the perfume industry. They could be a great alternative to water-based perfumes, without alcohol, and solve problems related to the oxidation and low bioavailability of fragrances with other non-alcoholic vehicles of perfumes like pomades or gels. The aim of our study was to develop stable Oil-in-Water (O/W) nanoemulsions that are compatible with selected fragrance compositions, without ethanol, polyols, and ionic surfactants, and to study their physicochemical, microbiological, and dermatological properties. The nano-perfume systems were obtained with a low-energy (Phase Inversion Composition; PIC) and with a high-energy (ultrasound, US) method, taking into account the possibility of moving from the laboratory scale to an industrial scale. The optimized nano-perfume formulations, prepared with different methods, yielded the same physicochemical properties (stability, medium droplet size of the inner phase, polydispersity, viscosity, surface tension, pH, density). Stable systems were obtained with a fragrance composition concentration within 6–15% range. These formulations had a low viscosity and a pH suitable for the skin. Moreover, the obtained results confirmed the protective role of nanoemulsions. The peroxide number measurement (POV) showed that the tested fragrance compositions had a high chemical stability. The results of the microbiological tests confirmed that the obtained products were free of microbiological contamination and were appropriately preserved. The dermatological test results confirmed the safety of the developed preparations.

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Section: Introductionmentioning

confidence: 99%

Preparation and Characterization of Water-Based Nano-Perfumes

et al. 2018

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“…For all parameters and storage times there are significant differences between WOR 10–25% microemulsions with droplets size of 53–67 nm that are visually transparent (Figure ) and WOR 30–50% samples with droplet size of 294–722 nm that are visually opaque. During storage for two weeks except to WORs 10 and 20% lightness in all samples were increased, which may be due to lowering droplet size at higher concnentrations of surfactant (Barzegar, Mehrnia, Nasehi, & Alipour, ). By increasing WOR lightness in all samples were increased which may be due to increasing droplet size and higher reflectance of light.…”

Section: Resultsmentioning

confidence: 94%

Preparation and characterization of water in sesame oil microemulsion by spontaneous method

Nazari¹,

Mehrnia²,

Jooyandeh³

et al. 2019

J Food Process Engineering

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Microemulsions based on their formation mechanism comparing to kinetically stable nanoemulsions are thermodynamically stable. Moreover, water in oil microemulsions could be used for encapsulation of water soluble compounds or preparing low fat products. In this research, we investigated the effects of preparation and formulation conditions on the formation and physical properties of water in sesame oil microemulsions using spontaneous method. Results showed that PGPR comparing to Span 80 formed transparent nanoemulsion with 67 nm droplet size. To investigate PGPR ability for emulsifying higher amounts of dispersed phase, water content increased in fixed concentration of PGPR. Increasing water content (%WOR) from 10 to 50% increased droplet size and viscosity from 53 to 722 nm and from 115 to 183 mPa.s, respectively. By increasing stirring speed to 900 rpm, droplet size decreased to 45 nm, but increasing stirring time to 2.5 hr, droplet size increased to 72 nm comparing to standard conditions. Comparing to pure water dissolving Vitamin C in inner aqueous phase increased droplet size to 171 nm. Practical applications Water in oil microemulsions fabricated using spontaneous method due to their high stability could be used for preparing low fat products such as seasonings and sauces. In this study, internal aqueous phase increased as much as possible at a fixed concentration of surfactant and factors affecting the emulsion droplet size and consequently their stability were evaluated. Moreover, such emulsions could be used for encapsulating water soluble ingredients such as Vitamin C in aqueous phase.

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“…The hydro-distillation method was used for the extractions (Clevenger-type apparatus). Oil-in-water (O/W) nanobactericides were prepared using a low-energy emulsification method (transition phase inversion approach) as defined by [ 32 , 33 ] with slight modifications. Tween 20 (Chemie-Link Sdn.…”

Section: Methodsmentioning

confidence: 99%

Ginger Essential Oils-Loaded Nanoemulsions: Potential Strategy to Manage Bacterial Leaf Blight Disease and Enhanced Rice Yield

et al. 2021

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The bacterial leaf blight (BLB) caused by Xanthomonas oryzae pv. oryzae (Xoo) is one of the most serious rice diseases, causing huge yield losses worldwide. Several technologies and approaches have been opted to reduce the damage; however, these have had limited success. Recently, scientists have been focusing their efforts on developing efficient and environmentally friendly nanobactericides for controlling bacterial diseases in rice fields. In the present study, a scanning electron microscope (SEM), transmission electron microscope (TEM), and a confocal laser scanning microscope (CLSM) were utilized to investigate the mode of actions of ginger EOs on the cell structure of Xoo. The ginger EOs caused the cells to grow abnormally, resulting in an irregular form with hollow layers, whereas the dimethylsulfoxide (DMSO) treatment showed a typical rod shape for the Xoo cell. Ginger EOs restricted the growth and production of biofilms by reducing the number of biofilms generated as indicated by CLSM. Due to the instability, poor solubility, and durability of ginger EOs, a nanoemulsions approach was used, and a glasshouse trial was performed to assess their efficacy on BLB disease control. The in vitro antibacterial activity of the developed nanobactericides was promising at different concentration (50–125 µL/mL) tested. The efficacy was concentration-dependent. There was significant antibacterial activity recorded at higher concentrations. A glasshouse trial revealed that developed nanobactericides managed to suppress BLB disease severity effectively. Treatment at a concentration of 125 μL/mL was the best based on the suppression of disease severity index, AUDPC value, disease reduction (DR), and protection index (PI). Furthermore, findings on plant growth, physiological features, and yield parameters were significantly enhanced compared to the positive control treatment. In conclusion, the results indicated that ginger essential oils loaded-nanoemulsions are a promising alternative to synthetic antibiotics in suppressing Xoo growth, regulating the BLB disease, and enhancing rice yield under a glasshouse trial.

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Fabrication of peppermint essential oil nanoemulsions by spontaneous method: Effect of preparing conditions on droplet size

Cited by 29 publications

References 18 publications

Preparation and Characterization of Water-Based Nano-Perfumes

Preparation and Characterization of Water-Based Nano-Perfumes

Preparation and characterization of water in sesame oil microemulsion by spontaneous method

Ginger Essential Oils-Loaded Nanoemulsions: Potential Strategy to Manage Bacterial Leaf Blight Disease and Enhanced Rice Yield

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