Fabrication of Polymerized Crystalline Colloidal Array Thin Film Modified β-Cyclodextrin Polymer for Paraoxon-ethyl and Parathion-ethyl Detection

Abstract

We have developed an optical chemical sensor for the detection of organophosphate (OP) compounds using a polymerized crystalline colloidal array (PCCA) thin film composed of a close-packed colloidal array of polystyrene particles. The PCCA thin film was modified with β-cyclodextrin (β-CD) polymer as a capping cavity for the selective detection of paraoxon-ethyl and parathion-ethyl chemical agents. The fabrication of the modified PCCA thin film was optimized and the structure was characterized using scanning electron microscopy (SEM). The arrangement of polystyrene particles in the PCCA follows a pattern of the fcc (111) planes with strong diffraction peak in the visible spectral region and pH dependence. The diffraction peak of the β-CD modified PCCA thin film showed a red shift according to the change of paraoxon-ethyl and parathion-ethyl concentrations at a fast response time (10 s) and high sensitivity with detection limits of 2.0 and 3.4 ppb, respectively. Furthermore, the proposed interaction mechanism of β-CD with paraoxon-ethyl and parathion-ethyl in the β-CD modified PCCA thin film were discussed.

Inclusion and Functionalization of Polymers with Cyclodextrins: Current Applications and Future Prospects

“…Magnetic solid phase extraction of rutin [55] Crosslinked polyvinyl alcohol/glutaraldehyde (PVA/GA) membranes with β-CD Textile liquid waste processing [56] PCCA thin film modified with β-CD polymer Capping cavity for the selective detection of paraoxon-ethyl and parathion-ethyl chemical agents [57] Cyclodextrin-based polymers have been shown to be efficient drug delivery materials; βCD-citric acid in-situ polymerization was used to functionalize two kinds of porous silicon (nanoporous and macroporous) that were used as matrices for drug release studies either in water or phosphate buffer solutions using ciprofloxacin and prednisolone as model drugs. Both cyclodextrin-based polymer composites showed better release control for drug delivery applications than non-functionalized silicon-β-CD-citric acid composite [46].…”

“…An optical chemical sensor for the detection of organophosphate (OP) compounds using a polymerized crystalline colloidal array (PCCA) thin film composed of a close-packed colloidal array of polystyrene particles was developed [57]. The PCCA thin film was modified with β-CD polymer as a capping cavity for the selective detection of paraoxon-ethyl and parathion-ethyl chemical agents.…”

Acetylcholinesterase-functionalized two-dimensional photonic crystals for the detection of organophosphates

“…10 Besides, we have previously demonstrated a molecularly imprinted photonic crystal (MIPC) to monitor the degradation product methyl phosphonic acid of the nerve agents including Sarin, Soman, VX and R-VX, with the corresponding LODs of 3. 27 However, some shortcomings of 3D-PC, such as time-consuming preparation and slow mass transfer ability, limit its applications as a simple and rapid chemical sensor.…”

“… 8,9 They also designed a β-cyclodextrin-modified polymerized crystalline colloidal array (PCCA) thin film to detect paraoxon-ethyl and parathion-ethyl with a quick response time (10 s) and high sensitivity with LODs of 2.0 and 3.4 ppb, respectively. 10 Besides, we have previously demonstrated a molecularly imprinted photonic crystal (MIPC) to monitor the degradation product methyl phosphonic acid of the nerve agents including Sarin, Soman, VX and R-VX, with the corresponding LODs of 3.5 × 10 −6 mol L −1 , 2.5 × 10 −5 mol L −1 , 7.5 × 10 −5 mol L −1 and 7.5 × 10 −5 mol L −1 , 11 which can also provide an indirect method to detect organophosphorus nerve agents.…”