Fabrication of polypyrrole nanoparticles through electrospraying

Monfared, Mostafa Rajabian; Tavanai, Hossein; Abdolmaleki, Amir; Morshed, Mohammad; Shamsabadi, Amir Shahin

doi:10.1088/2053-1591/ab3551

Cited by 4 publications

(3 citation statements)

References 39 publications

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“…Conversely, an optimal distance allows for good deposition efficiency and minimal agglomeration. 74,79 Moreover, varying the distance can also affect the porosity of the nanoparticles, with longer distances associated with increased porosity and shorter distances leading to decreased porosity. 92 The translation of the needle during the electrospraying process is another factor that influences the size, morphology, deposition efficiency, and porosity of the nanoparticles.…”

Section: Effect Of Process Parametersmentioning

confidence: 99%

“…Several studies have investigated the influence of solvent selection on nanoparticle synthesis. For instance, Monfared et al observed that solvents with higher conductivity resulted in the production of smaller and more uniform nanoparticles during electrospray processes 79 . Similarly, Boda et al found that solvent conductivity affected the size and distribution of nanoparticles formed by electrospray deposition 9 .…”

Section: Electrosprayingmentioning

confidence: 99%

“…When the distance is too close, nanoparticle agglomeration can occur, leading to poor deposition efficiency. Conversely, an optimal distance allows for good deposition efficiency and minimal agglomeration 74,79 . Moreover, varying the distance can also affect the porosity of the nanoparticles, with longer distances associated with increased porosity and shorter distances leading to decreased porosity 92 …”

Section: Electrosprayingmentioning

confidence: 99%

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Review on electrospray nanoparticles for drug delivery: Exploring applications

Patel,

Haemmerich

2024

Polymers for Advanced Techs

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Electrospraying has emerged as a versatile technique in the pharmaceutical field due to its potential in drug delivery and formulation. With its advantages of cost‐effectiveness, reproducibility, ease of operation, and scalability, electrospraying offers numerous benefits for pharmaceutical applications. Notably, the production of nanoparticles using electrospraying provides unique properties, including small size, drug encapsulation capabilities, biocompatibility, and scalability. Electrospray nanoparticles have demonstrated significant promise in various drug delivery routes, such as oral and topical administration. These nanoparticles enhance drug stability, protection, and permeability, effectively overcoming limitations associated with these routes. Moreover, electrospray nanoparticles have proven valuable in targeted drug delivery, improving drug bioavailability and efficacy. Their ability to penetrate tissues and cells enables enhanced drug delivery to specific sites within the body. Additionally, electrospray nanoparticles can be tailored with targeting ligands or responsive components for controlled release and combination therapy, exhibiting successful applications in cancer treatment and neurological disorders. Therefore, electrospray nanoparticle technology shows great promise in biomedical applications, offering a versatile platform for targeted drug delivery and therapeutic interventions. This comprehensive review examines the various drug delivery applications of electrospraying and provides insights into its possibilities and challenges. The paper discusses the principles, methods, and parameters of electrospraying, while also exploring its use in fabricating drug delivery systems, addressing poorly soluble drugs. By synthesizing the findings from multiple studies, this review offers a comprehensive understanding of electrospraying's current state and potential in the pharmaceutical industry.

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Section: Effect Of Process Parametersmentioning

confidence: 99%

Section: Electrosprayingmentioning

confidence: 99%