We prove that among all flag homology 5-manifolds with n vertices, the join of 3 circles of as equal length as possible is the unique maximizer of all the face numbers. The same upper bounds on the face numbers hold for 5-dimensional flag Eulerian normal pseudomanifolds.Conjecture 1.1 (Nevo-Petersen, [11]). The γ-vector of any flag homology sphere satisfies Frankl-Füredi-Kalai inequalities (see [4]). If this conjecture holds, then the face numbers of flag (2m − 1)spheres with n vectices are simultaneously maximized by the face numbers of J m (n).Conjecture 1.2 [8]). In the class of flag homology (2m − 1)-spheres with n vectices, J m (n) is the unique maximizer of all the face numbers.