“Face of the Giant Panda” Sign in Wilson Disease

Atalar, Mehmet Haydar; Baspinar, Nisa

doi:10.4274/tnd.2019.60863

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2023

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“…The MRI abnormalities characteristic of WD in the midbrain reveals the “face of the giant panda,” a second miniature “panda face” can be seen in the high signal abnormality in the pons. These are rare findings and were also absent in our case 12 …”

Section: Discussionsupporting

confidence: 59%

See 1 more Smart Citation

Magnetic resonance imaging pontine signal abnormality in neurological Wilson disease: A case report

Gajurel,

Karki,

Parajuli

et al. 2023

Clinical Case Reports

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Key Clinical MessageWD is diagnosed with the help of a brain MRI, which frequently reveals hyperintensities in the lentiform nucleus. But occasionally, high signals can be seen in the pons, thalamus, and midbrain.AbstractWilson disease is a rare inherited disorder due to impaired copper excretion. The brain MRI mainly shows hyperintensities in the lentiform nucleus. We report the case of an 18 years old female diagnosed with neurological Wilson disease, presenting with uncommon brain MRI hyperintensities, predominantly in the pons, thalamus, and midbrain.

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Section: Discussionsupporting

confidence: 59%

“…These are rare findings and were also absent in our case. 12 Multiple medications are approved for treating WD, such as D-penicillamine, trientine, and zinc salts. Our patient received D-penicillamine, zinc, and pyridoxine therapy starting at a low dose, with neurological symptoms monitored.…”

Section: Discussionmentioning

confidence: 99%