Facial and neural mechanisms during interactive disclosure of biographical information

Cañigueral, Roser; Zhang, Xian; Noah, J. Adam; Tachtsidis, Ilias; Hamilton, Antonia F. de C.; Hirsch, Joy

doi:10.1016/j.neuroimage.2020.117572

Cited by 17 publications

(14 citation statements)

References 79 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We suggest using the optical signal strength as an exclusion criterion when performing applied research (e.g., robot control by a BCI and clinical studies) and reporting the level of raw signal strength in future publications. Performing screening prior to a neuroscientific study has been proposed, 70 – 72 and metrics related to signal quality, such as the scalp coupling index, 73 the light-tissue coupling index, 74 or the signal quality index, 75 could be adapted. Second, MWs showed a significant effect on

-values, with all subjects with low MW amplitudes exhibiting high

-values, thereby confirming the relevant literature.…”

Section: Discussionmentioning

confidence: 99%

Characterizing reproducibility of cerebral hemodynamic responses when applying short-channel regression in functional near-infrared spectroscopy

et al. 2022

View full text Add to dashboard Cite

. Significance: Functional near-infrared spectroscopy (fNIRS) enables the measurement of brain activity noninvasively. Optical neuroimaging with fNIRS has been shown to be reproducible on the group level and hence is an excellent research tool, but the reproducibility on the single-subject level is still insufficient, challenging the use for clinical applications. Aim: We investigated the effect of short-channel regression (SCR) as an approach to obtain fNIRS measurements with higher reproducibility on a single-subject level. SCR simultaneously considers contributions from long- and short-separation channels and removes confounding physiological changes through the regression of the short-separation channel information. Approach: We performed a test-retest study with a hand grasping task in 15 healthy subjects using a wearable fNIRS device, optoHIVE. Relevant brain regions were localized with transcranial magnetic stimulation to ensure correct placement of the optodes. Reproducibility was assessed by intraclass correlation, correlation analysis, mixed effects modeling, and classification accuracy of the hand grasping task. Further, we characterized the influence of SCR on reproducibility. Results: We found a high reproducibility of fNIRS measurements on a single-subject level ( and correlation ). SCR increased the reproducibility from 0.64 to 0.81 ( ) but did not affect classification (85% overall accuracy). Significant intersubject variability in the reproducibility was observed and was explained by Mayer wave oscillations and low raw signal strength. The raw signal-to-noise ratio (threshold at 40 dB) allowed for distinguishing between persons with weak and strong activations. Conclusions: We report, for the first time, that fNIRS measurements are reproducible on a single-subject level using our optoHIVE fNIRS system and that SCR improves reproducibility. In addition, we give a benchmark to easily assess the ability of a subject to elicit sufficiently strong hemodynamic responses. With these insights, we pave the way for the reliable use of fNIRS neuroimaging in single subjects for neuroscientific research and clinical applications.

show abstract

-values, with all subjects with low MW amplitudes exhibiting high

-values, thereby confirming the relevant literature.…”

Section: Discussionmentioning

confidence: 99%

Characterizing reproducibility of cerebral hemodynamic responses when applying short-channel regression in functional near-infrared spectroscopy

et al. 2022

View full text Add to dashboard Cite

show abstract

“… 338 , 339 Quantification of dyadic properties includes measures of neural coupling, sometimes referred to as inter-brain synchrony or cross-brain coherence, 340 – 342 which quantifies the extent to which the temporal patterns of neural signals across brains are correlated. 321 , 343 – 345 The main questions include: What are these dyadic mechanisms? How can they be isolated?…”

Section: Functional Applications In Neurodevelopment and Cognitionmentioning

confidence: 99%

Optical imaging and spectroscopy for the study of the human brain: status report

et al. 2022

Self Cite

View full text Add to dashboard Cite

. This report is the second part of a comprehensive two-part series aimed at reviewing an extensive and diverse toolkit of novel methods to explore brain health and function. While the first report focused on neurophotonic tools mostly applicable to animal studies, here, we highlight optical spectroscopy and imaging methods relevant to noninvasive human brain studies. We outline current state-of-the-art technologies and software advances, explore the most recent impact of these technologies on neuroscience and clinical applications, identify the areas where innovation is needed, and provide an outlook for the future directions.

show abstract

“…A previous two-person fMRI study of nonverbal communication [ 28 ] reported brain-to-brain coupling between a “sender” and “perceiver” of facial expressions in a set of regions, including the insula, ventro-/dorsolateral PFC, precuneus, and hippocampus. In addition, a functional near infrared spectroscopy (fNIRS) hyperscanning study reported increased facial expressivity and eye gaze, which was underpinned by activation and cross-brain coupling of vlPFC, dlPFC, and the TPJ, when participants were sharing personal information interactively, relative to a nonsharing condition [ 58 ]. These studies support the importance of such social-mirroring circuitry to interpersonal interactions.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, while participants in this study were real clinicians and real patients with chronic pain, the MRI environment is inherently limited in terms of ecological validity due to the supine position of participants and the inability to communicate verbally during the pain/treatment fMRI scan. Future studies may investigate facial communication and brain-to-brain concordance using electroencephalography [ 63 ] or near-infrared spectroscopy [ 58 ], which would enable a more naturalistic patient–clinician interaction with more mobility, though at the cost of lower spatial resolution and depth. Finally, the clinical context in this study may not generalize to other kinds of patient–clinician interactions (e.g., psychotherapy, general medicine, and physical therapy).…”

Section: Discussionmentioning

confidence: 99%

Patient–clinician brain concordance underlies causal dynamics in nonverbal communication and negative affective expressivity

et al. 2022

View full text Add to dashboard Cite

Patient–clinician concordance in behavior and brain activity has been proposed as a potential key mediator of mutual empathy and clinical rapport in the therapeutic encounter. However, the specific elements of patient–clinician communication that may support brain-to-brain concordance and therapeutic alliance are unknown. Here, we investigated how pain-related, directional facial communication between patients and clinicians is associated with brain-to-brain concordance. Patient–clinician dyads interacted in a pain-treatment context, during synchronous assessment of brain activity (fMRI hyperscanning) and online video transfer, enabling face-to-face social interaction. In-scanner videos were used for automated individual facial action unit (AU) time-series extraction. First, an interpretable machine-learning classifier of patients’ facial expressions, from an independent fMRI experiment, significantly distinguished moderately painful leg pressure from innocuous pressure stimuli. Next, we estimated neural-network causality of patient-to-clinician directional information flow of facial expressions during clinician-initiated treatment of patients’ evoked pain. We identified a leader–follower relationship in which patients predominantly led the facial communication while clinicians responded to patients’ expressions. Finally, analyses of dynamic brain-to-brain concordance showed that patients’ mid/posterior insular concordance with the clinicians’ anterior insula cortex, a region identified in previously published data from this study1, was associated with therapeutic alliance, and self-reported and objective (patient-to-clinician-directed causal influence) markers of negative-affect expressivity. These results suggest a role of patient-clinician concordance of the insula, a social-mirroring and salience-processing brain node, in mediating directional dynamics of pain-directed facial communication during therapeutic encounters.

show abstract

Facial and neural mechanisms during interactive disclosure of biographical information

Cited by 17 publications

References 79 publications

Characterizing reproducibility of cerebral hemodynamic responses when applying short-channel regression in functional near-infrared spectroscopy

Characterizing reproducibility of cerebral hemodynamic responses when applying short-channel regression in functional near-infrared spectroscopy

Optical imaging and spectroscopy for the study of the human brain: status report

Patient–clinician brain concordance underlies causal dynamics in nonverbal communication and negative affective expressivity

Contact Info

Product

Resources

About