Facile and one pot synthetic routes for various novel, differently fused and promising heteropolycycles

Hemi-Synthesis of Chiral Imine, Benzimidazole and Benzodiazepines from Essential Oil of Ammodaucus leucotrichus subsp. leucotrichus

“…Benzodiazepines represent a well-known class of therapeutics displaying anticonvulsant, anti-inflammatory, analgesic and anti-depressive effects [ 19 ]. A literature survey reveals that a fair amount of work has been published in the stereospecific synthesis of benzodiazepine derivatives by the condensation of aldehydes and several heterocyclic compounds [ 20 , 21 ]. In particular, a simple and fast method has recently been described by us for the elaboration of novel benzodiazepine structures [ 22 ].…”

Introducing an Effective Nanocatalytic for the One-Pot Synthesis and Investigation of Biological Properties of Pyranopyrimidinone and Xanthene Derivatives

“…Pyranopyrimidinone and xanthene derivatives are widely used in pharmaceutical chemistry [1]. This group of organic compounds have various pharmaceutical activities such as antiviral2, antibacterial3, antitumor [4], hepatoprotective [5], antifungal activities [6], in the food industry as additives [7] and anti-inflammatory properties [8]. In order to synthesize this class of compounds, several methods have been reported, including the reaction of the palladium-catalysed cyclisation [9][10][11][12], different Lewis acids such as NbCl2 [13][14][15][16] and Brønsted acids [17][18][19][20].…”

Antioxidant, Antimicrobial and Antiproliferative Activities of Synthesized 2,2,5,5-Tetramethyl-9-aryl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione Derivatives

“…A wide variety of methods for the preparation of the xanthenes have been reported. [6][7][8][9][10][11] Antioxidants are necessary to control degenerative reactions produced by reactive oxygen and nitrogen species. These species are involved in several ailments including cancer, heart diseases and Alzheimer's disease.…”