Facile aqueous synthesis of functionalized CdTe nanoparticles and their application as fluorescence probes for determination of adenine and guanine

Li, Li; LuYaxiang,; DingYaping,; ZhangFenfen,; WangYaping,

doi:10.1139/v11-144

Cited by 16 publications

(4 citation statements)

References 38 publications

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“…The detection principle is unique in that the fluorescence of CDs is first quenched upon addition of copper ions, Cu 2+ , followed by fluorescence recovery when guanine is introduced in the CD-Cu 2+ system. The work claimed a simple, facile, and one-step microwave-assisted preparation method, yet the sensor displayed a LOD of 0.67 × 10 −8 mol L −1 , much lower than those reported in other published works [ 206 ]. Moreover, the CD-Cu 2+ -based sensor evidently showed high selectivity toward guanine compared to other bases such as adenine, uracil, cytosine, and thymine.…”

Section: Sensing Applicationsmentioning

confidence: 63%

Biogreen Synthesis of Carbon Dots for Biotechnology and Nanomedicine Applications

2018

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Over the past decade, carbon dots have ignited a burst of interest in many different fields, including nanomedicine, solar energy, optoelectronics, energy storage, and sensing applications, owing to their excellent photoluminescence properties and the easiness to modify their optical properties through doping and functionalization. In this review, the synthesis, structural and optical properties, as well as photoluminescence mechanisms of carbon dots are first reviewed and summarized. Then, we describe a series of designs for carbon dot-based sensors and the different sensing mechanisms associated with them. Thereafter, we elaborate on recent research advances on carbon dot-based sensors for the selective and sensitive detection of a wide range of analytes, including heavy metals, cations, anions, biomolecules, biomarkers, nitroaromatic explosives, pollutants, vitamins, and drugs. Lastly, we provide a concluding perspective on the overall status, challenges, and future directions for the use of carbon dots in real-life sensing.

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Section: Sensing Applicationsmentioning

confidence: 63%

Biogreen Synthesis of Carbon Dots for Biotechnology and Nanomedicine Applications

2018

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“…CdTe nanoparticles have also been developed for the detection of adenine and guanine, through the functionalization with thioglycolic acid (TGA), but so far only synthetic probes have been used for the validation of these fluorescence probes ( Li et al, 2012 ).…”

Section: Functionalization Methodsmentioning

confidence: 99%

Latest Trends in Lateral Flow Immunoassay (LFIA) Detection Labels and Conjugation Process

Mirica

Stan²,

Chelcea³

et al. 2022

Front. Bioeng. Biotechnol.

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LFIA is one of the most successful analytical methods for various target molecules detection. As a recent example, LFIA tests have played an important role in mitigating the effects of the global pandemic with SARS-COV-2, due to their ability to rapidly detect infected individuals and stop further spreading of the virus. For this reason, researchers around the world have done tremendous efforts to improve their sensibility and specificity. The development of LFIA has many sensitive steps, but some of the most important ones are choosing the proper labeling probes, the functionalization method and the conjugation process. There are a series of labeling probes described in the specialized literature, such as gold nanoparticles (GNP), latex particles (LP), magnetic nanoparticles (MNP), quantum dots (QDs) and more recently carbon, silica and europium nanoparticles. The current review aims to present some of the most recent and promising methods for the functionalization of the labeling probes and the conjugation with biomolecules, such as antibodies and antigens. The last chapter is dedicated to a selection of conjugation protocols, applicable to various types of nanoparticles (GNPs, QDs, magnetic nanoparticles, carbon nanoparticles, silica and europium nanoparticles).

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“…In recent years, a variety of methods including high-performance liquid chromatogrphy, ion-pairing liquid chromatography, micellar electrokinetic chromatography, electrochemistry, capillary electrophoresis, chemiluminescence, spectrophotometry, surface enhanced Raman scattering and mass spectrometry have been developed for the determination and quantification of adenine (Ad) in biological fluids [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27]. In fact, these analytic methods were thought to be rapid and sensitive, but they also have several shortcomings such as high cost, high time consumption, tedious pretreatment steps and poor capture ability to substrates.…”

Section: Introductionmentioning

confidence: 99%

Design and synthesis of novel adenine fluorescence probe based on Eu(III) complexes with dtpa-bis(guanine) ligand

Tian

Jiang

Dou

et al. 2017

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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A novel adenine (Ad) fluorescence probe (Eu-dtpa-bis(guanine)) was designed and synthesized by improving experimental method based on the Eu(III) complex and dtpa-bis(guanine) ligand. The dtpa-bis(guanine) ligand was first synthesized by the acylation action between dtpaa and guanine (Gu), and the corresponding Eu(III) complex was successfully prepared through heat-refluxing method with dtpa-bis(guanine) ligand. As a novel fluorescence probe, the Eu-dtpa-bis(guanine) complex can detect adenine (Ad) with characteristics of strong targeting, high specificity and high recognition ability. The detection mechanism of the adenine (Ad) using this probe in buffer solution was studied by ultraviolet-visible (UV-vis) and fluorescence spectroscopy. When the Eu-dtpa-bis(guanine) was introduced to the adenine (Ad) solution, the fluorescence emission intensity was significantly enhanced. However, adding other bases such as guanine (Gu), xanthine (Xa), hypoxanthine (Hy) and uric acid (Ur) with similar composition and structure to that of adenine (Ad) to the Eu-dtpa-bis(guanine) solution, the fluorescence emission intensities are nearly invariable. Meanwhile, the interference of guanine (Gu), xanthine (Xa), hypoxanthine (Hy) and uric acid (Ur) on the detection of the adenine using Eu-dtpa-bis(guanine) probe was also studied. It was found that presence of these bases does not affect the detection of adenine (Ad). A linear response of fluorescence emission intensities of Eu-dtpa-bis(guanine) at 570nm as a function of adenine (Ad) concentration in the range of 0.00-5.00×10molL was observed. The detection limit is about 4.70×10molL.

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Facile aqueous synthesis of functionalized CdTe nanoparticles and their application as fluorescence probes for determination of adenine and guanine

Cited by 16 publications

References 38 publications

Biogreen Synthesis of Carbon Dots for Biotechnology and Nanomedicine Applications

Biogreen Synthesis of Carbon Dots for Biotechnology and Nanomedicine Applications

Latest Trends in Lateral Flow Immunoassay (LFIA) Detection Labels and Conjugation Process

Design and synthesis of novel adenine fluorescence probe based on Eu(III) complexes with dtpa-bis(guanine) ligand

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