Facile Bacterial Cellulose Nanofibrillation for the Development of a Plasmonic Paper Sensor

Purwidyantri, Agnes; Karina, Myrtha; Hsu, Chen-Ming; Srikandace, Yoice; Prabowo, Briliant Adhi; Lai, Chao‐Sung

doi:10.1021/acsbiomaterials.9b01890

Cited by 20 publications

(11 citation statements)

References 49 publications

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“…Another popular method to avoid the requirement of an electric pump in the microfluidic system is the capillary-driven chip [11,[14][15][16]. The capillary attraction can be driven by porous or cellulose materials, such as thread, woven fabrics, paper [17][18][19][20][21][22], and cellulose sponges [16,23,24]. Besides the low-cost and environmentally friendly materials, the cellulose-based capillarity also has a practical feature to handle liquid waste after the experiments.…”

Section: Introductionmentioning

confidence: 99%

A pump-free microfluidic device for fast magnetic labeling of ischemic stroke biomarkers

2022

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This research proposes a low-cost and simple operation microfluidic chip to enhance the magnetic labeling efficiency of two ischemic stroke biomarkers: cellular fibronectin (c-Fn) and matrix metallopeptidase-9 (MMP9). This fully portable and pump-free microfluidic chip is operated based on capillary attractions without any external power source and battery. It uses an integrated cellulose sponge to absorb the samples. At the same time, a magnetic field is aligned to hold the target labeled by the magnetic nanoparticles (MNPs) in the pre-concentrated chamber. By using this approach, the specific targets are labeled from the beginning of the sampling process without preliminary sample purification. The proposed study enhanced the labeling efficiency from 1 hr to 15 min. The dynamic interactions occur in the serpentine channel, while the crescent formation of MNPs in the pre-concentrated chamber, acting as a magnetic filter, improves the biomarker-MNP interaction. The labeling optimization by the proposed device influences the dynamic range by optimizing the MNP ratio to fit the linear range across the clinical cutoff value. The limit of detection (LOD) of 2.8 ng/mL and 54.6 ng/mL of c-Fn measurement were achieved for undiluted and four times dilutions of MNP, respectively. While for MMP9, the LODs were 11.5 ng/mL for undiluted functionalized MNP and 132 ng/mL for four times dilutions of functionalized MNP. The results highlight the potential use of this device for clinical sample preparation and specific magnetic target labeling.When combined with a detection system could also be used as an integrated component of a point-of-care platform.

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Section: Introductionmentioning

confidence: 99%

A pump-free microfluidic device for fast magnetic labeling of ischemic stroke biomarkers

2022

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“…Several attempts were reported to use biodegradable materials for biochemical sensing components. A paper and bio-cellulose (BC) substrates were proposed for biosensor researches, such as for electro-optical biosensor for herbicide monitoring [18], for surface-enhanced Raman spectroscopy (SERS) sensor [14], [19], [20], microfluidic paper for human urine screening [21], electrochemical sensors [22], potentiometric ion sensing [23], colorimetric paper-based biosensors for the detection spike protein SARS-CoV-2 [24].…”

Section: Biocellulose-based Componentsmentioning

confidence: 99%

“…The great advantage for the utilization of textile-or thread-based biosensors components is very low-cost fabrication compared to the other sensing such as the solid state-based materials. The only necessary process is the material functionalization for the specific purpose of Reprinted with permission from [14]. Copyright 2020 American Chemical Society.…”

Section: Biocellulose-based Componentsmentioning

confidence: 99%

Environmentally Friendly and Biodegradable Components for Biosensors

Prabowo

Purwidyantri

2022

IEEE Nanotechnology Mag.

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The pandemic of coronavirus diseases 2019 (COVID-19) attracts dramatic attention worldwide that biosensing technology plays an essential role in screening, tracing, and diagnostics of the diseases in society. The World Health Organization (WHO) recommends the significant features of biosensor development, called ASSURED: affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and delivered to the end-user. Consequently, the practical, low-cost, and environmentally friendly components of biosensors are urgently required in the future for such cases of massive tests in homecare and point of care. This article reviews the emerging trend and applications of recent biosensor research utilizing reusable and biodegradable components. The challenges of future development were discussed to overview the consideration of the subsequent research roadmap.

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“…In this case, CNM can be used as flexible platform with multilayer and 3D nanonetworks for the immobilization of metallic nanoparticles, minimizing agglomeration and aggregation effects. Thus, the role of CNM can be used not only as a sensing layer but also as a flexible, stabilizing support that allows the uniform distribution of nanoparticles on its surface. ,,, For instance, in the study reported by Nabeela et al, the authors investigated the role of CNF in increasing the SERS signal in the detection of organophosphate pesticide methyl parathion. Plasmonic silver nanoconstructs obtained using CNF were able to produce sensors with sensitivity higher than that obtained with neat silver nanoparticles.…”

Section: Role and Performance Of Cellulose Nanomaterials In Sensorsmentioning

confidence: 99%

A Review on the Role and Performance of Cellulose Nanomaterials in Sensors

et al. 2021

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Sensors and biosensors play a key role as an analytical tool for the rapid, reliable, and early diagnosis of human diseases. Such devices can also be employed for monitoring environmental pollutants in air and water in an expedited way. More recently, nanomaterials have been proposed as an alternative in sensor fabrication to achieve gains in performance in terms of sensitivity, selectivity, and portability. In this direction, the use of cellulose nanomaterials (CNM), such as cellulose nanofibrils (CNF), cellulose nanocrystals (CNC), and bacterial cellulose (BC), has experienced rapid growth in the fabrication of varied types of sensors. The advantageous properties are related to the supramolecular structures that form the distinct CNM, their biocompatibility, and highly reactive functional groups that enable surface functionalization. The CNM can be applied as hydrogels and xerogels, thin films, nanopapers and other structures interesting for sensor design. Besides, CNM can be combined with other materials (e.g., nanoparticles, enzymes, carbon nanomaterials, etc.) and varied substrates to advanced sensors and biosensors fabrication. This review explores recent advances on CNM and composites applied in the fabrication of optical, electrical, electrochemical, and piezoelectric sensors for detecting analytes ranging from environmental pollutants to human physiological parameters. Emphasis is given to how cellulose nanomaterials can contribute to enhance the performance of varied sensors as well as expand novel sensing applications, which could not be easily achieved using standard materials. Finally, challenges and future trends on the use of cellulose-based materials in sensors and biosensors are also discussed.

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Facile Bacterial Cellulose Nanofibrillation for the Development of a Plasmonic Paper Sensor

Cited by 20 publications

References 49 publications

A pump-free microfluidic device for fast magnetic labeling of ischemic stroke biomarkers

A pump-free microfluidic device for fast magnetic labeling of ischemic stroke biomarkers

Environmentally Friendly and Biodegradable Components for Biosensors

A Review on the Role and Performance of Cellulose Nanomaterials in Sensors

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