Facile design of plant-oil-infused fine surface asperity for transparent blood-repelling endoscope lens

Nishioka, Sachiko; Tenjimbayashi, Mizuki; Manabe, Kengo; Matsubayashi, Takeshi; Suwabe, Ken; Tsukada, Kosuke; Shiratori, Seimei

doi:10.1039/c6ra08390k

Cited by 30 publications

(48 citation statements)

References 44 publications

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“…Such excellent transparency is inseparable from the presence of water environment. At the interface of two different medium with the refractive indexes of n 1 and n 2 , respectively, the reflectance, R 12 , can be described as

R_{12} = {(\frac{n_{1} - n_{2}}{n_{1} + n_{2}})}^{2}

…”

Section: Femtosecond Laser‐induced Underwater Superoleophobicitymentioning

confidence: 99%

A Review of Femtosecond‐Laser‐Induced Underwater Superoleophobic Surfaces

Yong

Chen

Yang

et al. 2018

Adv Materials Inter

101

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R_{12} = {(\frac{n_{1} - n_{2}}{n_{1} + n_{2}})}^{2}

…”

Section: Femtosecond Laser‐induced Underwater Superoleophobicitymentioning

confidence: 99%

A Review of Femtosecond‐Laser‐Induced Underwater Superoleophobic Surfaces

Yong

Chen

Yang

et al. 2018

Adv Materials Inter

101

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“…The characteristics of liquid-infused coatings may provide a potential solution to mitigate the performance concerns in endoscopes, especially because methodologies have been developed to create transparent coatings with efficient liquid repellency (16,(20)(21)(22)27). Here, we design and explore the function of a liquid-infused coating applied on a bronchoscope lens during clinically relevant procedures.…”

Section: Significancementioning

confidence: 99%

Transparent antifouling material for improved operative field visibility in endoscopy

Sunny

Cheng

Daniel

et al. 2016

Proc. Natl. Acad. Sci. U.S.A.

122

125

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Camera-guided instruments, such as endoscopes, have become an essential component of contemporary medicine. The 15–20 million endoscopies performed every year in the United States alone demonstrate the tremendous impact of this technology. However, doctors heavily rely on the visual feedback provided by the endoscope camera, which is routinely compromised when body fluids and fogging occlude the lens, requiring lengthy cleaning procedures that include irrigation, tissue rubbing, suction, and even temporary removal of the endoscope for external cleaning. Bronchoscopies are especially affected because they are performed on delicate tissue, in high-humidity environments with exposure to extremely adhesive biological fluids such as mucus and blood. Here, we present a repellent, liquid-infused coating on an endoscope lens capable of preventing vision loss after repeated submersions in blood and mucus. The material properties of the coating, including conformability, mechanical adhesion, transparency, oil type, and biocompatibility, were optimized in comprehensive in vitro and ex vivo studies. Extensive bronchoscopy procedures performed in vivo on porcine lungs showed significantly reduced fouling, resulting in either unnecessary or ∼10–15 times shorter and less intensive lens clearing procedures compared with an untreated endoscope. We believe that the material developed in this study opens up opportunities in the design of next-generation endoscopes that will improve visual field, display unprecedented antibacterial and antifouling properties, reduce the duration of the procedure, and enable visualization of currently unreachable parts of the body, thus offering enormous potential for disease diagnosis and treatment.

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“…The resultant SLIPS still exhibited slippery property even after immersing in seawater for two months or being severely abraded by sandpaper. Nishioka et al fabricated a SLIPS coated endoscope lens based on the self‐assembly of methyl group modified silica nanoparticles . Since the SLIPS could prevent blood and other body fluids from adhering on the lens surface, the visibility through such endoscope maintained clear for a very long time when it was used to inspect the internal organs of a mouse.…”

mentioning

confidence: 99%

“…Constructing 3D porous network microstructures is a critical step toward achieving SLIPS but it is not an easy thing; most current technologies seem powerless to this kind of microstructure, especially for those top‐down methods. Until now, most reported porous networks to prepare SLIPS are based on “deposition/coating” methods which are typical bottom‐up techniques . The porous networks formed during the nanofibers and nanoparticles depositing/coating on a substrate.…”

mentioning

confidence: 99%

“…In this work, bending/abrasion resistance of the femtosecond laser‐induced PA6 SLIPS were tested and the results were shown in Figure . For the SLIPSs that are fabricated by typical bottom‐up methods (e.g., depositing/coating methods), their porous network layer and substrate are usually not same material . Therefore, the deposited nanofibers and nanoparticles easily fall off if the SLIPSs are bent, because the internal force distribution between the porous layer and the substrate is not uniform, resulting in a degradation of liquid‐repellent ability.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Nepenthes Inspired Design of Self‐Repairing Omniphobic Slippery Liquid Infused Porous Surface (SLIPS) by Femtosecond Laser Direct Writing

Yong

Chen

Yang

et al. 2017

Adv Materials Inter

149

105

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In this Communication, femtosecond laser is first used to successfully fabricate a slippery liquid infused porous surface (SLIPS). A kind of 3D porous network microstructure can be directly created on polyamide‐6 (PA6) substrate by a one‐step femtosecond laser direct writing method. The preparation process of SLIPS mainly includes three steps: femtosecond laser ablation, fluoroalkyl layer modification, and infusion of lubricating liquid. The porous layer and the substrate layer of this as‐prepared SLIPS are inherent one material. Such SLIPS has many advantages over the most reported SLIPS fabricated based on “deposition/coating” methods whose porous layers are foreign materials against the substrates. A broad range of liquids including water, hexadecane, lake water, ink, glycerol, coffee, milk, egg white, and egg yolk can easily slide down the 10° tilted SLIPS, revealing that the resultant SLIPS has excellent liquid‐repellent ability. Even though the SLIPS suffers from heavily physical damage, the surface can rapidly self‐repair without any additional treatment and obtain slippery property again. The developed SLIPS promises to contribute to the achievement of omniphobic materials in self‐cleaning, antifouling, biomedical devices, and fuel transport.

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Facile design of plant-oil-infused fine surface asperity for transparent blood-repelling endoscope lens

Abstract: Minimally invasive medical operations, especially endoscope operations, have attracted much attention and play a major role in modern medicine.

Cited by 30 publications

References 44 publications

A Review of Femtosecond‐Laser‐Induced Underwater Superoleophobic Surfaces

A Review of Femtosecond‐Laser‐Induced Underwater Superoleophobic Surfaces

Transparent antifouling material for improved operative field visibility in endoscopy

Nepenthes Inspired Design of Self‐Repairing Omniphobic Slippery Liquid Infused Porous Surface (SLIPS) by Femtosecond Laser Direct Writing

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