Facile fabrication of pH-controlled drug release mat via engineering 3D reversible gel-like nanofibers

Liao, Xueyang; Xiang, Zhenyu; Lei, Ying; Zhu, Zijun; Guo, Junling; Song, Lin; Shang, Jiaojiao

doi:10.1016/j.polymer.2022.124925

Cited by 2 publications

(3 citation statements)

References 21 publications

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“…In alkaline conditions, the copolymer deswelled, becoming hydrophilic, which caused the fibers to contract and retain the encapsulated substances. In practical terms, when loaded with amoxicillin, the nanofibers showed a significant release of the drug (around 40% at pH 5.8 and 35% at pH 6.4), in contrast to a reduced release of the drug at pH 7.4 and pH 8.5 (12% and 8%, respectively) after 84 h [31].…”

Section: Phmentioning

confidence: 96%

“…This adaptability is crucial as each stimulus provides a unique avenue for customizing structure properties and responses to specific needs. These structures find application across various domains such as wearable and smart textiles [24], water filtration [30], biomedicine [31], biomimetics [26], among others. In these applications, the fibrous structures exhibit versatile behaviors in response to environmental stimulus, showcasing functions like color changes [22], shape changes [32], self-cleaning processes [33], or perform other tailored responses.…”

Section: Responsive Fibrous Structuresmentioning

confidence: 99%

“…• C, using HRP, H 2 O 2, ACAC, DMAPS, MBA, and phosphate buffer; washing and air-drying of the fabric Synthesis of PDMA through radical polymerization, at 70 • C, using DEAEMA and MMA as monomers, ABP as cross-linking agents, and AIBN as the thermal initiator, followed by dialysis; electrospinning of solutions containing PDMA, DMF, THF and amoxicillin; UV irradiation and drying of the nanofiber mats Biomedical[31] ABP: 4-acryloyl benzophenone; ACAC: acetylacetone; APS: ammonium persulfate; BDO:1,4-butanediol; BN: boron nitride; BTCA: 1,2,3,4-butanetetracarboxylic acid; CB: cholesteryl benzoate; COC: cholesteryl oleyl carbonate; CP: cholesteryl pelargonate; DEAP: 2,2-diethoxyacetophenone; DMAPS: N,N-dimethyl (methacryloylethyl) ammonium propane sulfonate; EG: ethylene glycol; EGDMA: ethylene glycol dimethacrylate; HEMA: 2-hydroxyethylmethacrylate; HEVAH: 2-hydroxyethyl-6-(vinyl amino)hexanoate; HPγCD: hydroxypropyl-γcyclodextrin; HRP: horseradish peroxidase; Irgacure D-2959: 2-hydroxy-4-(2-hydroxyethoxy)-2-methylpropiophenone; KH-570: 3-(trimethoxysilyl) propyl methacrylate; LA: lauric acid; LC: liquid crystal; LLC: lyotropic liquid crystals; LMA: laurylmethacrylate; MBA: N,N'-methylene bis(acrylamide); MDI: 4,4 ′ -diphenylmethane diisocyanate; nBA: n-butyl acrylate; NWF: nonwoven fiber mat; ODMA-MAA: n-octadecyl methacrylate-methacrylic acid; OSA: octadecenyl succinic anhydride; PHA: poly (1,6-hexanediol adipate); PHEVAH: poly(2-hydroxyethyl-6-(vinyl amino)hexanoate); P(MEO 2 MA-co-OEGMA 500 : poly(diethylene glycol monomethyl ether methacrylate-co-poly(ethylene glycol) methyl ether methacrylate; PVA: poly(vinyl alcohol); SBMA: [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl); SDS: sodium dodecyl sulphate; SHP: sodium hypophosphite; THF: tetrahydrofuran; TMSPMA:…”

mentioning

confidence: 99%

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Fibrous Structures: An Overview of Their Responsiveness to External Stimuli towards Intended Application

Ferreira,

Gonçalves,

Antunes

et al. 2024

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In recent decades, the interest in responsive fibrous structures has surged, propelling them into diverse applications: from wearable textiles that adapt to their surroundings, to filtration membranes dynamically altering selectivity, these structures showcase remarkable versatility. Various stimuli, including temperature, light, pH, electricity, and chemical compounds, can serve as triggers to unleash physical or chemical changes in response. Processing methodologies such as weaving or knitting using responsive yarns, electrospinning, as well as coating procedures, enable the integration of responsive materials into fibrous structures. They can respond to these stimuli, and comprise shape memory materials, temperature-responsive polymers, chromic materials, phase change materials, photothermal materials, among others. The resulting effects can manifest in a variety of ways, from pore adjustments and altered permeability to shape changing, color changing, and thermal regulation. This review aims to explore the realm of fibrous structures, delving into their responsiveness to external stimuli, with a focus on temperature, light, and pH.

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Section: Phmentioning

confidence: 96%

Section: Responsive Fibrous Structuresmentioning

confidence: 99%

mentioning

confidence: 99%

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Fibrous Structures: An Overview of Their Responsiveness to External Stimuli towards Intended Application

Ferreira,

Gonçalves,

Antunes

et al. 2024

Polymers

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Recent Progress in Stimuli-Responsive Antimicrobial Electrospun Nanofibers

Mercante,

Teodoro,

dos Santos

et al. 2023

Polymers

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Electrospun nanofibrous membranes have garnered significant attention in antimicrobial applications, owing to their intricate three-dimensional network that confers an interconnected porous structure, high specific surface area, and tunable physicochemical properties, as well as their notable capacity for loading and sustained release of antimicrobial agents. Tailoring polymer or hybrid-based nanofibrous membranes with stimuli-responsive characteristics further enhances their versatility, enabling them to exhibit broad-spectrum or specific activity against diverse microorganisms. In this review, we elucidate the pivotal advancements achieved in the realm of stimuli-responsive antimicrobial electrospun nanofibers operating by light, temperature, pH, humidity, and electric field, among others. We provide a concise introduction to the strategies employed to design smart electrospun nanofibers with antimicrobial properties. The core section of our review spotlights recent progress in electrospun nanofiber-based systems triggered by single- and multi-stimuli. Within each stimulus category, we explore recent examples of nanofibers based on different polymers and antimicrobial agents. Finally, we delve into the constraints and future directions of stimuli-responsive nanofibrous materials, paving the way for their wider application spectrum and catalyzing progress toward industrial utilization.

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Facile fabrication of pH-controlled drug release mat via engineering 3D reversible gel-like nanofibers

Cited by 2 publications

References 21 publications

Fibrous Structures: An Overview of Their Responsiveness to External Stimuli towards Intended Application

Fibrous Structures: An Overview of Their Responsiveness to External Stimuli towards Intended Application

Recent Progress in Stimuli-Responsive Antimicrobial Electrospun Nanofibers

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