Facile Microwave Synthesis of Pd-Catalyzed Suzuki Reaction for Bis-6-Aryl Imidazo[1,2-a]Pyridine-2-Carboxamide Derivatives with PEG3 Linker

Regioselective Pd-Catalyzed Suzuki–Miyaura Borylation Reaction for the Dimerization Product of 6-Bromoimidazo[1,2-a]pyridine-2-carboxylate: Mechanistic Pathway, Cytotoxic and Tubercular Studies

“…This method enabled the synthesis of novel adducts by employing borylation after linker addition with the use of small boranes. 42 In this second report, details of the regioselective product formation and consequences during synthesis are reported, as outlined in Schemes 1-3. The key starting material i.e., ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate (3), was synthesized by reaction of 5-bromopyridin-2amine (1) with ethyl bromopyruvate (2) in ethanol using an ultrasonicator (Scheme 1).…”

“…As the aromatic systems have become increasingly functional and widely used, research on their synthesis has focused on the application of C-C bond-formation reactions using name reactions like Suzuki and Heck coupling reactions, [37][38][39][40][41][42] Sonogashira coupling, 43 and cross-coupling reactions. 44 Although each of the C-C coupling pathways has one or more limitation, one of the most widely used catalytic methods is Suzuki-Miyaura borylation.…”

An efficient protocol for the synthesis of substituted 5‐amino pyrazole bearing benzo[d]imidazolone Core and their antioxidant activity

“…Our group is continuously working to generate a new scaffold based on nitrogen-rich heterocycles and to identify lead in the thrust area of medicinal chemistry in which a real "Hitmen" like molecules are synthesized by applying hybridization of two or more active heterocycles concept [20][21][22][23][24]. Herein, we report the four-step synthetic strategy starting from easily accessible substrate, that is, methyl 3,4-diaminobenzoate to afford the high yielded regioselective adducts, 5-(5-amino-1H-pyrazol-3-yl)-1,-3-dimethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one derivatives (5a-l).…”

HAuCl4 Catalyzed and Dibenzyl amine Centered A3 coupling reaction: Synthesis, Spectroscopic Proofing and Anti‐microbial Efficacy

“…Consequently, heterogeneous catalysts that may be recovered can play a role in the prevention or minimization of chemical wastes, especially in the context of large‐scale and industrial processes [22] . This study focuses on the synthesis of A 3 adducts of amines, aldehydes, and alkynes in relation to the described issues and as a continuation of our research in the green chemistry domain [23–26] . By including DBA as one of the colliding species, the Au salt acts as a catalyst to speed up the synthesis process proposed.…”

“…[22] This study focuses on the synthesis of A 3 adducts of amines, aldehydes, and alkynes in relation to the described issues and as a continuation of our research in the green chemistry domain. [23][24][25][26] By including DBA as one of the colliding species, the Au salt acts as a catalyst to speed up the synthesis process proposed. The primary benefit of the recycled gold composite is that it may be used again and again without significant performance degradation.…”