Facile radiochemical separation of clinical-grade 90Y from 90Sr by selective precipitation for targeted radionuclide therapy

Chakravarty, Rubel; Chakraborty, Sudipta; Jadhav, Sachin; Dash, Ashutosh

doi:10.1016/j.nucmedbio.2019.01.002

Cited by 13 publications

(8 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Partitioning of radioactive 137 Cs ( t 1/2 ≈ 30.2 years) and 90 Sr ( t 1/2 ≈ 28.8 years) from high-level liquid waste (HLLW) is highly desirable to reduce the burden on the geological repository , and minimize the adverse impact on the environment and health. , More significantly, this contributes to the recovery of 137 Cs and 90 Sr as specific radiation and heat sources for medical and technological applications. , Separation between 137 Cs and 90 Sr is the key process for such purpose. Currently, solvent extraction using macrocyclic ligands such as crown ether , and calixcrown , has shown high selectivity to a certain substance ( 137 Cs or 90 Sr) and thus brings about a considerable separation efficiency.…”

Section: Introductionsupporting

confidence: 90%

“…( 5) AgSnSe-1 exhibits remarkable stability over a wide pH range of 1−12, and the leaching of Se is negligible upon ion exchange. (6) The Cs + exchange performance is slightly affected by coexisting Na + , Mg 2+ , and Ca 2+ cations. (7) The Cs + ion exchanged product can be conveniently eluted for recycling use.…”

Section: ■ Conclusionmentioning

confidence: 98%

“…3,4 More significantly, this contributes to the recovery of 137 Cs and 90 Sr as specific radiation and heat sources for medical and technological applications. 5,6 Separation between 137 Cs and 90 Sr is the key process for such purpose. Currently, solvent extraction using macrocyclic ligands such as crown ether 7,8 and calixcrown 9,10 has shown high selectivity to a certain substance ( 137 Cs or 90 Sr) and thus brings about a considerable separation efficiency.…”

Section: ■ Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Efficient Cs⁺–Sr²⁺ Separation over a Microporous Silver Selenidostannate Synthesized in Deep Eutectic Solvent

et al. 2020

View full text Add to dashboard Cite

Efficient Cs+–Sr2+ separation, highly desirable for radionuclide recovery in medical and industrial applications, was achieved by the ion exchange technique over a novel microporous silver selenidostannate, [NH3CH3]0.5[NH2(CH3)2]0.25Ag1.25SnSe3 (AgSnSe-1). This material was synthesized in deep eutectic solvent (DES), where the alkylammonium cations play significant structure-directing roles in the construction of micropores that allow for selective ion exchange toward Cs+ against Sr2+. The much greater K d Cs (1.06 × 104 mL g–1) over K d Sr (87.7 mL g–1) contributes to an outstanding separation factor SF Cs/Sr of ∼121.4 that is top-ranked among inorganic materials. An ion exchange column filled with AgSnSe-1 exhibits a remarkable separation effect for 10 000 bed volumes of continuous flow, with removal rates of ∼99.9% and ∼0 ± 5.5% for Cs+ and Sr2+, respectively. AgSnSe-1 exhibits excellent β and γ radiation resistances and a chemical stability over a broad pH range of 1–12. The Se leaching level below the safe guideline value for drinking water highlights the environmental-friendly nature of AgSnSe-1. The high Cs+ exchange performance is almost unaffected by Na+, Mg2+, and Ca2+ cations. The Cs+-laden product AgSnSe-1Cs can be facilely eluted for recycling use, highlighting the great potential of open framework metal selenides in nuclear waste treatment and renewable energy utilization.

show abstract

Section: Introductionsupporting

confidence: 90%

Section: ■ Conclusionmentioning

confidence: 98%

Section: ■ Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Efficient Cs⁺–Sr²⁺ Separation over a Microporous Silver Selenidostannate Synthesized in Deep Eutectic Solvent

et al. 2020

View full text Add to dashboard Cite

show abstract

“…[7][8][9] As for 90 Sr, its secular decay to carrier free 90 Y (β-emitter, t 1/2 = 64 h) contributes to a convenient but reliable radionuclide generator system for the preparation of 90 Y-based radiopharmaceuticals which are widely used for molecule radiolabeling in the treatment of cancer as well as in radiation synoviorthesis. [10][11][12] To purify these radionuclides, it necessitates a highly selective extration of objective ion, either Cs + or Sr 2+ , against the other competitor from a homogeneous system.…”

mentioning

confidence: 99%

pH‐Controlled Switch over Coadsorption and Separation for Mixed Cs⁺ and Sr²⁺ by an Acid‐Resistant Potassium Thioantimonate

Zhao

Cheng

Wang

et al. 2022

Adv Funct Materials

View full text Add to dashboard Cite

Switchable coadsorption and separation for elimination/partitioning of Cs + and Sr 2+ is achieved by pH-controlled ion exchange using a potassium thioantimonate K 2 Sb 4 S 7 •2H 2 O (SbS-1K) with fantastic pH durability from diluted NaOH (pH 12) to concentrated HCl (3 m). At pH 6, SbS-1K exhibits ultrafast adsorption kinetics (R ≈ 90% in 2 min for Cs + and 20 min for Sr 2+ ) and high removal rates (R ≈ 98-99%) at equilibrium for both Cs + and Sr 2+ . At pH 2, the Sr 2+ adsorption is inhibited by H + with a great loss in R Sr to 11.18%, whereas the R Cs remains at 96.99%, contributing to a top-ranked separation factor SF Cs/Sr of 256. The SbS-1K-filled ion exchange column can be switched between the eliminating (R Cs > 99.91%; R Sr > 98.19%) and separating (R Cs > 98.99%; R Sr ≈ 0±3%) modes for treating continuous flow with a variation from pH 6 to pH 2 or vice versa. The SbS-1K/PTFE membrane exhibits coadsorption and separation effects for filtration of low concentrated mixed Cs + and Sr 2+ solution (1 ppm for each), even at an ultrafast vacuum filtration speed (30 mL min -1 ). Combined with easy synthesis and high β/γ irradiation resistance, SbS-1K represents a new-concept bifunctional exchanger with discriminating intelligence for equipment innovation.

show abstract

“…On the other hand, the high radioactivity and heat-generating property make 90 Sr amenable for medical and technological applications. For instance, upon emitting a β particle, the 90 Sr converts to carrier free 90 Y ( t 1/2 ≈ 64 h) which has been widely utilized for peptide receptor radionuclide therapy, radiation synovectomy, and intra-arterial radioembolization therapy. − In addition, 90 Sr fuelled thermoelectric generators are used in several countries to power unmanned weather data acquisition systems, lighthouses, and other navigation aids, etc . Consequently, the separation of 90 Sr from nuclear waste solution not only is essential for public healthy and environmental concerns but also bears importance for alternate medical and industrial uses.…”

Section: Introductionmentioning

confidence: 99%

Effective and Rapid Adsorption of Sr²⁺ Ions by a Hydrated Pentasodium Cluster Templated Zinc Thiostannate

et al. 2019

View full text Add to dashboard Cite

Separation of 90Sr from radioactive wastewater not only is essential for human public health and environmental remediation but also bears importance for alternate medical and industrial applications. Here, we report the facile synthesis of an open framework zinc thiostannate, Na5Zn3.5Sn3.5S13·6H2O (ZnSnS-1), templated by hydrated pentasodium clusters. This compound exhibits an effective and rapid ion exchange property for Sr2+ ions. The exchange kinetics conforms to a pseudo-second-order model, implying that the chemical adsorption of Sr2+ may be the rate-determining step. According to the Langmuir–Freundlich isotherm, the maximum exchange capacity of ZnSnS-1 for Sr2+ is 124.2 mg/g and ranks ahead of those of all the reported metal sulfide Sr2+ adsorbents. High exchange performance is observed over the broad pH range 2.5–13, although it could be inhibited to some extent by coexisting ions, especially Na+ and Ca2+. ZnSnS-1 shows a higher affinity for Sr2+ compared to Cs+, and the performance is almost unaffected by the presence of coexisting Cs+ even in excess amounts. Importantly, the Sr2+ in the exchanged product can be conveniently eluted by a concentrated KCl solution, and the recycled exchanger can be further used for Sr2+ exchange. These advantages combined with the robust framework for recycling concerns make ZnSnS-1 a highly promising exchanger for removal of radioactive Sr from the liquid nuclear waste.

show abstract

Facile radiochemical separation of clinical-grade 90Y from 90Sr by selective precipitation for targeted radionuclide therapy

Cited by 13 publications

References 26 publications

Efficient Cs⁺–Sr²⁺ Separation over a Microporous Silver Selenidostannate Synthesized in Deep Eutectic Solvent

Efficient Cs⁺–Sr²⁺ Separation over a Microporous Silver Selenidostannate Synthesized in Deep Eutectic Solvent

pH‐Controlled Switch over Coadsorption and Separation for Mixed Cs⁺ and Sr²⁺ by an Acid‐Resistant Potassium Thioantimonate

Effective and Rapid Adsorption of Sr²⁺ Ions by a Hydrated Pentasodium Cluster Templated Zinc Thiostannate

Contact Info

Product

Resources

About

Facile radiochemical separation of clinical-grade 90Y from 90Sr by selective precipitation for targeted radionuclide therapy

Cited by 13 publications

References 26 publications

Efficient Cs+–Sr2+ Separation over a Microporous Silver Selenidostannate Synthesized in Deep Eutectic Solvent

Efficient Cs+–Sr2+ Separation over a Microporous Silver Selenidostannate Synthesized in Deep Eutectic Solvent

pH‐Controlled Switch over Coadsorption and Separation for Mixed Cs+ and Sr2+ by an Acid‐Resistant Potassium Thioantimonate

Effective and Rapid Adsorption of Sr2+ Ions by a Hydrated Pentasodium Cluster Templated Zinc Thiostannate

Contact Info

Product

Resources

About

Efficient Cs⁺–Sr²⁺ Separation over a Microporous Silver Selenidostannate Synthesized in Deep Eutectic Solvent

Efficient Cs⁺–Sr²⁺ Separation over a Microporous Silver Selenidostannate Synthesized in Deep Eutectic Solvent

pH‐Controlled Switch over Coadsorption and Separation for Mixed Cs⁺ and Sr²⁺ by an Acid‐Resistant Potassium Thioantimonate

Effective and Rapid Adsorption of Sr²⁺ Ions by a Hydrated Pentasodium Cluster Templated Zinc Thiostannate