Facile regioselective synthesis of novel bioactive thiazolyl-pyrazoline derivatives via a three-component reaction and their antimicrobial activity

Microwave-Assisted Synthesis of Tetrahydrocarbazole Linked 1,2-Diazoles in Aqueous-Brønsted Acid Catalytic System

“…Therefore, to attain benchmark reaction conditions in microwave, ketone ( c), benzaldehyde ( a), and hydrazine hydrate ( a) in 1 : 1 : 1.2 equivalents were exposed to microwave radiations at 300 W. It has been observed that microwave-assisted Aza-Michael reaction proceeds more speedily in acetic acid-water catalytic system than in water alone. This led to exploring various combinations of catalytic system [17].…”

A cesium fluoride promoted efficient and rapid multicomponent synthesis of functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives

“…The methodology has emerged as a powerful synthetic tool for the preparation of biologically active compounds and important drugs [1,2]. The multicomponent reactions have been used frequently in organic synthesis, and significant attempts have been focused on the design and development of environmentally friendly and less expensive methods for the generation of libraries of heterocyclic compounds [3,4].…”

Alternate Method for the Dimerization of 2-Benzylidene inden-1-one Derivatives: Synthesis of 1,3-Diaryl-1,3,3a,8a-tetrahydro-8H-spiro[cyclopenta[a]indene-2,2'-indene]-1',8(3'H)-diones

“…Besides the biological activity they are chemically very active compounds because they contain α,β-unsaturated carbonyl system on structures. Therefore, many heterocyclic and polyfunctional compounds can be synthesized easily starting from chalcones or chalcone like compounds [2]. 2-Benzylidene inden-1-one derivatives are chalcone type compounds and their bioactive potentials are quite high.…”