Facile silicone oil-coated hydrophobic surface for surface enhanced Raman spectroscopy of antibiotics

Usman, Muhammad; Guo, Xin; Wu, Qiusheng; Barman, Jitesh; Su, Shaoqiang; Huang, Bingru; Zhang, Zhang; Zhan, Qiuqiang

doi:10.1039/c9ra00817a

Cited by 22 publications

(15 citation statements)

References 34 publications

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“…The cocrystal in the common plate was small and dispersive, while that in the coated plate was larger and irregularly accumulated. The enriched effect of the hydrophobic silicon dioxide surface indirectly improves the sensitivity of the instrument by forming spots with higher sample concentrations on the plate [ 10 ]. As a result, the coated plate achieves a better spectrum by manually searching for the “sweet point.” This feature of the coated plate is particularly beneficial in samples where it is difficult to attain a good spectrum and is very much dependent on searching for a “sweet point.”…”

Section: Resultsmentioning

confidence: 99%

A New Silicon Dioxide-Coated MALDI-ToF Sample Plate for Peptide Analysis

Huang¹,

Sun

et al. 2020

BioMed Research International

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In this report, we describe the development and testing of a new coated plate which improves the sensitivity and accuracy in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF-MS). The coated plate was covered with a thin layer of hydrophobic silicon dioxide, which enabled sample enrichment due to the water repellent nature of the silicon dioxide surface. Sensitivity and required laser strengths were tested using peptide standards, with the results that these coated plates required lower laser power and showed increased sensitivity than that of common plates. Accuracy was tested using bacteria, saliva, and serum samples. The coated plates showed significantly increased degrees of accuracy through their capacity to reduce mass shift. The importance and necessity of accuracy analysis in the assessment of new sample plates, which is rarely described in other papers, is also discussed.

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Section: Resultsmentioning

confidence: 99%

A New Silicon Dioxide-Coated MALDI-ToF Sample Plate for Peptide Analysis

Huang¹,

Sun

et al. 2020

BioMed Research International

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“…The LOD values of ciprofloxacin could be achieved at 10 −9 mol/L, and clear Raman characteristic peaks still were observed at the lowest concentration, which was better than the results reported in the literature. Based on the literature, the Raman spectral vibration peaks in ciprofloxacin were assigned and identified [30,31]. For example, the characteristic peak in the 635-695 cm −1 range was due to the out-of-plane vibrations of the ring.…”

Section: Application For Detection Of Ciprofloxacinmentioning

confidence: 99%

Three-Dimensional Dendritic Au–Ag Substrate for On-Site SERS Detection of Trace Molecules in Liquid Phase

Shao

Niu

et al. 2022

Nanomaterials

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The development of a facile surface-enhanced Raman scattering (SERS) sensor for the on-site detection of trace molecules in liquid phase is a compelling need. In this paper, a three-dimensional (3D) dendritic Au–Ag nanostructure was constructed by a two-step electro displacement reaction in a capillary tube for the on-site liquid phase detection of trace molecules. The multiplasmon resonance mechanism of the dendritic Au–Ag structure was simulated using the finite-difference time domain (FDTD) method. It was confirmed that the highly branched 3D structure promoted the formation of high-density “hot spots” and interacted with the gold nanoparticles at the dendrite tip, gap, and surface to maximize the spatial electric field, which allowed for high signal intensification to be observed. More importantly, the unique structure of the capillary made it possible to achieve the on-site detection of trace molecules in liquids. Using Rhodamine 6G (R6G) solution as a model molecule, the 3D dendritic Au–Ag substrate exhibited a high detection sensitivity (10−13 mol/L). Furthermore, the developed sensor was applied to the detection of antibacterial agents, ciprofloxacin (CIP), with clear Raman characteristic peaks observed even at concentrations as low as 10−9 mol/L. The results demonstrated that the 3D dendritic Au–Ag sensor could successfully realize the rapid on-site SERS detection of trace molecules in liquids, providing a promising platform for ultrasensitive and on-site liquid sample analysis.

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“…It can provide unique fingerprint information of analyte molecules in a short time [11]. Usman et al prepared slippery-SERS substrates to detect NOR [12]. However, the low repeatability of SERS detection is still a current concern.…”

Section: Introductionmentioning

confidence: 99%

Free-Standing Membrane Liquid-State Platform for SERS-Based Determination of Norfloxacin in Environmental Samples

Liu

Zhou

et al. 2021

J. Anal. Test.

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Surface-enhanced Raman scattering (SERS) has been widely used in various fields due to high sensitivity, but it is hindered by its low repeatability. Here, we explored a highly reproducible free-standing liquid-state platform (FSM) for monitoring norfloxacin (NOR) in the environmental field. After optimizing the types of nanoparticles (NPs) and pH value in NOR solution, the relative standard deviation (RSD) of FSM SERS analysis can be stabilized below 10% (n ≥ 8), and the R 2 of the calibration curve in the range of 20 µg/L-100 µg/L was 0.995. In addition, the results showed that the limit of detection (LOD) (3σ/k) of NOR was 1.3 µg/L. Moreover, the NOR in the spiked samples was successfully quantified by FSM, and the recovery rate exceeded 95%. The proposed method has the potential for rapid analysis of drug residues in environmental samples.

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Facile silicone oil-coated hydrophobic surface for surface enhanced Raman spectroscopy of antibiotics

Abstract: The proposed facile, cost-effective slippery surface and gold nanorods based combinational approach for the SERS detection technique is a powerful strategy for the trace detection of the aqueous pollutant analytes even at very low concentrations.

Cited by 22 publications

References 34 publications

A New Silicon Dioxide-Coated MALDI-ToF Sample Plate for Peptide Analysis

A New Silicon Dioxide-Coated MALDI-ToF Sample Plate for Peptide Analysis

Three-Dimensional Dendritic Au–Ag Substrate for On-Site SERS Detection of Trace Molecules in Liquid Phase

Free-Standing Membrane Liquid-State Platform for SERS-Based Determination of Norfloxacin in Environmental Samples

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