Facile synthesis of 2D Al-TCPP MOF nanosheets for efficient sonodynamic cancer therapy

Abstract

Two-dimensional (2D) metal-organic framework (MOF) nanosheets have been widely explored as diagnostic and therapeutic reagents for cancer therapy, including photodynamic therapy, chemodynamic therapy, radiation therapy, and catalytic therapy, in recent...

Effective antibacterial action of a 2D bimetallic Al/Fe-TCPP NMOF loaded with glucose oxidase by a cascade catalytic reaction and depleting glutathione simultaneously

“…S1, ESI †) was synthesized according to previous reports. 23 Then, Fe 3+ was introduced into the Al-TCPP NMOF to obtain a bimetallic Al/Fe-TCPP NMOF. The TEM, SEM, and AFM images (Fig.…”

Catalyzing Generation and Stabilization of Oxygen Vacancies on CeO2−x Nanorods by Pt Nanoclusters as Nanozymes for Catalytic Therapy

“…[43][44][45][46][47][48][49] Importantly, defect engineering has also been demonstrated to be a promising approach to activate/optimize the performance of metal oxide/hydroxide nanomaterials for biomedical applications such as photodynamic therapy, sonodynamic therapy, and catalytic therapy in last few years. [50][51][52][53][54][55] As a typical example, we have first reported the significant boosting the photodynamic therapy performance of 2D LDH nanosheets by defect engineering induced by simple acidic etching, [52] which was further extended to sonodynamic therapy in a later study. [53] Elemental doping or guest intercalation has also been developed as effective ways to induce rich defect engineering on layered MoO 3 , thus significantly improving their performance when used as nanozymes in catalytic therapy.…”

Gelothermal Synthesis of Monodisperse MIL‐88A Nanoparticles with Tunable Sizes and Metal Centers for Potential Bioapplications

“…cations. [3][4][5][6][7][8][9] The utility as nanomedicines, however, requires MOFs to be downsized from polydisperse bulk crystals to monodisperse nanoparticles so as to produce consistent and reliable performance. [10] During the past few years, various synthetic strategies have been developed for miniaturization, for example, the technique-assistant (microwave, ultrasound, spray drying, microfluidic reactor, etc.)…”