“…Sulphonylation. 4,5-Dihydro-3,5-diaryl-1-(4-fluorophenylsulphonyl)pyrazoles 341 and 2-aryl-1-(4-fluorphenylsulphonyl)indoles 343 were prepared from reaction of 4-fluorophenylsulphonyl chloride 339 with the appropriate 4,5-dihydro-3,5-diarylpyrazoles 340 or 2-arylindoles 342, via solid-liquid phase (THF/KOH/TBAB) [107] (Figure 121). N-Sulphonylation product 346 was prepared through treating 2-chloro-6,6-difluro-1,3-dioxolo[4,5-f]benzimidazole 344 with 3,5-dimethylisoxazole-4-sulphonyl chloride 345 via PTC protocol (toluene/aq.…”