Facile Synthesis of Iron-Based MOFs MIL-100(Fe) as Heterogeneous Catalyst in Kabachnick Reaction

Abstract

An effective technique was proposed for the synthesis of novel α-aminophosphonates: a three-component one-pot condensation reaction of aniline, aromatic aldehydes, and triphenyl phosphite in the presence of (MIL-100(Fe)) as a heterogeneous catalyst. Initially, MIL-100(Fe) was synthesized using H3BTC and ferric nitrate at low temperature and atmospheric pressure. Further, MIL-100(Fe) was characterized using various techniques such as XRD, BET surface area, scanning electron microscopy (SEM), Fourier-transform infrared (FT-IR), and thermogravimetric analysis (TGA). Herein, MIL-100(Fe) showed exceptional catalytic performance for the synthesis of α-aminophosphonate and its derivatives compared with conventional solid catalysts, and even homogeneous catalysts. The study demonstrated that MIL-100(Fe) is an ecofriendly and easily recyclable heterogeneous catalyst in Kabachnick reactions for α-aminophosphonate synthesis, with high yield (98%) and turnover frequency (TOF ~ 3.60 min−1) at room temperature and a short reaction time (30 min).

Study on Chloroquine phosphate loading capacity of MIL-100(Fe) synthesized by sonochemical method

“…The crystallinity of the material was investigated by X-ray diffraction (Figure 4). The results show that the obtained materials have characteristic peaks at 11 o , 19 o , 24 o , and 28 o , which are similar to those previously reported [23,24]. The height of the peak is low, and the peak width is large because the material is synthesized by sonochemical method, which makes the crystals to be formed quickly.…”

Hematite nanoparticle decorated MIL-100 for the highly selective and sensitive electrochemical detection of trace-level paraquat in milk and honey

“…Metal-organic frameworks (MOFs) have shown satisfactory results and prospects in many fields due to their excellent chemical functionality, modifiable morphology, pore structure and high specific surface area. MOF materials are now widely used in electrochemistry [18], adsorption [19], separation [20], multiphase catalysis [21], and drug delivery [22]. Among them, MIL-100(Fe) is used as a transition metal MOF, which has two different mesoporous cages (2.5 and 2.9 nm).…”

Green-Synthesized HF-free MIL-100(Fe) Nanoparticle-Infused Chitosan Mixed-Matrix Membranes for Enhanced CO2 Permeance

“…The diffraction planes found at 2 theta values of 5.18, 10.09, 19.05, 23.03°, and 27.29° were matched with the crystallographic database (CCDC standard no. 640536), ,, which corresponds to the cubic (isometric) crystal. , The XRD spectra of the MOF confirm the successful formation of MIL-100­(Fe) NPs, synthesized under low-temperature and HF-free conditions. As shown in the Raman spectra in Figure c, the unique MIL-100­(Fe) peaks in the 0–1800 cm –1 region can be seen in typical MOF .…”