Facile synthesis of mesoporous carbon aerogel for the removal of ibuprofen from aqueous solution by central composite experimental design (CCD)

Abolhasani, Sara; Ahmadpour, Ali; Bastami, Tahereh Rohani; Yaqubzadeh, Alireza

doi:10.1016/j.molliq.2019.02.084

Cited by 60 publications

(14 citation statements)

References 45 publications

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“…To overcome these problems, many researches are employing response surface methodology (RSM) to optimise the adsorption process. RSM is a combined statistical and mathematical method that uses the polynomial equation to study the relationship between the numerous independent parameters and also one or more responses [36]. Compared to conventional optimisation technique, RSM reduces the time and cost involved [37].…”

Section: Design Of Experimentsmentioning

confidence: 99%

Process optimisation of methylene blue sequestration onto physical and chemical treated coffee husk based adsorbent

Murthy

Gowrishankar

2020

SN Appl. Sci.

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Coffee husk (CH) was physically and chemically treated with autoclaving (SCH) and NaOH (NCH) to develop low-cost adsorbent for the removal of methylene blue (MB) from synthetic wastewater, and their adsorption efficiencies were evaluated in batch mode. The prepared adsorbent was characterised by SEM, FTIR and point of zero charge. The central composite rotatable design (CCRD) was employed to optimise the adsorption process parameters such as pH, adsorbent dosage and initial MB concentration. The second-order quadratic model fitted best with the experimental adsorption data, and ANOVA results showed that the developed model was significant. The linear terms in the model significantly influence the adsorption capacity of SCH and NCH, but interaction terms were not significant. At optimised conditions, the developed adsorbents can remove > 90% of MB from the aqueous solution. Freundlich model showed a better fit with the adsorption isotherm data with R 2 greater than 0.95. Kinetics of MB adsorption onto SCH and NCH followed the pseudo-second-order model. The maximum monolayer adsorption capacity was found to be 129 and 200 mg/g for SCH and NCH, respectively. The present study showed that pretreated coffee husk waste can be used as an alternative for expensive adsorbents for the removal of dyes from wastewater.

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Section: Design Of Experimentsmentioning

confidence: 99%

Process optimisation of methylene blue sequestration onto physical and chemical treated coffee husk based adsorbent

Murthy

Gowrishankar

2020

SN Appl. Sci.

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“…Although there are many studies about the degradation of IBU, only a few focuses on optimization. Such studies include the removal of IBU by absorption using mesoporous carbon aerogel [18], photooxidation of IBU using thin films of PAA/PAH/TiO 2 [19], nano-photocatalytic degradation of IBU by using Ultraviolet C/ZnO [20], IBU degradation by a three-dimensional electro-Fenton process [21], and sonoelectrochemical oxidation of IBU [22]. Thus, based on the literature survey, it can be concluded that the electrochemical degradation of IBU is feasible but needs to be optimized to reduce the overall cost of the process.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Mineralization of Ibuprofen on BDD Electrodes in an Electrochemical Flow Reactor: Numerical Optimization Approach

et al. 2020

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Statistical analysis was applied to optimize the electrochemical mineralization of ibuprofen with two boron-doped diamond (BDD) electrodes in a continuous electrochemical flow reactor under recirculation batch mode. A central composite rotatable (CCR) experimental design was used to analyze the effect of initial pH (2.95–13.04), current intensity (2.66–4.34 A), and volumetric flow rate (0.16–1.84 L/min) and further optimized by response surface methodology (RSM) to obtain the maximum mineralization efficiency and the minimum specific energy consumption. A 91.6% mineralization efficiency (EM) of ibuprofen with a specific energy consumption (EC) of 4.36 KW h/g TOC within 7 h of treatment was achieved using the optimized operating parameters (pH0 = 12.29, I = 3.26 A, and Q of 1 L/min). Experimental results of RSM were fitted via a third-degree polynomial regression equation having the performance index determination coefficients (R2) of 0.8658 and 0.8468 for the EM and EC, respectively. The reduced root-mean-square error (RMSE) was 0.1038 and 0.1918 for EM and EC, respectively. This indicates an efficient predictive performance to optimize the operating parameters of the electrochemical flow reactor with desirability of 0.9999993. Besides, it was concluded that the optimized conditions allow to achieve a high percentage of ibuprofen mineralization (91.6%) and a cost of 0.002 USD $/L. Therefore, the assessed process is efficient for wastewater remediation.”

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“…As a result, it may be inferred that the obtained residuals have the expected scattering and that the proposed model is adequate. 44 Cook's distance value less than 0.50 (<0.50) demonstrates that our model is free of effect points 45,46 (Figure 3e).…”

Section: Statistical Analysis and Model Fittingmentioning

confidence: 90%

In vitro‐studies of adenosine‐ β‐cyclodextrin inclusion complexes loaded into chitosan, sodium alginate and bentonite‐based nanocomposite optimized by RSM as a sustained release system

Khushbu

Jindal

2022

J of Applied Polymer Sci

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Drugs with less aqueous solubility and permeability acquire significant hurdles in designing safe and effective formulations. The purpose of this study was to prepare an adenosine (ADS): β-cyclodextrin (β-CD) inclusion complex that could be consistently incorporated into a nanocomposite system for topical administration. Several procedures, including kneading, microwave irradiation, and co-precipitation, were used to develop an adenosine: β-CD inclusion complex. ROESY, DSC, XRD, and 1 H NMR spectroscopy were used to analyze the adenosine-β-CD inclusion complex. Then bentonite (BN) incorporated chitosan (CH) and sodium alginate (ALG) nanocomposite were synthesized by microwave irradiation method. Response Surface Methodology (RSM) design was executed to optimize the reaction parameters. The Minimum Resolution V design was implemented to find significant variables to get maximum percentage swelling. The inclusion complexes of ADS: β-CD were directly loaded into the CH/ALG/BN nanocomposite and the adenosine release was analyzed in simulated intestinal fluids (SIF) and simulated gastric fluids (SGF). Five kinetic models were investigated to know about the drug release mechanism. After a 24-h interval, the ADS final release was 86 ppm at pH 2, 96 ppm at pH 7, and 85 ppm at pH 7.4. Bentonite has a layered structure that allows it to introduce the drug molecule into its cavity, resulting in sustainable adenosine release. The exploratory kinetic analysis demonstrated that β-CD influences polymer relaxation, resulting in slow release.

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Facile synthesis of mesoporous carbon aerogel for the removal of ibuprofen from aqueous solution by central composite experimental design (CCD)

Cited by 60 publications

References 45 publications

Process optimisation of methylene blue sequestration onto physical and chemical treated coffee husk based adsorbent

Process optimisation of methylene blue sequestration onto physical and chemical treated coffee husk based adsorbent

Electrochemical Mineralization of Ibuprofen on BDD Electrodes in an Electrochemical Flow Reactor: Numerical Optimization Approach

In vitro‐studies of adenosine‐ β‐cyclodextrin inclusion complexes loaded into chitosan, sodium alginate and bentonite‐based nanocomposite optimized by RSM as a sustained release system

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