Facile Synthesis of Unsymmetrically Substituted Ferrocene-1,1 ’ -bis- Carboxamides via Homogeneous Catalytic Carbonylation

Formation of intramolecular hydrogen bonds in heterodisubstituted ferrocene diamides with a secondary and a tertiary amido group: X-ray structure of 1′-(N′-butyl-carbamoyl)-morpholino ferrocenecarboxamide

“…(1)) [13] or in one pot, using two different amines as nucleophiles simultaneously (Eq. (2)) [12]. In the present work the second method was found to be superior and several heterodisubstituted ferrocene diamides (e.g.…”

“…1d [12] and 1e [13] have been characterized before. Compounds 2a-d were obtained as side products, so for these compounds no yields are indicated here.…”

“…Recently, we have reported on the homogeneous catalytic synthesis of various ferrocene amides and diamides starting from iodoferrocene and 1,1 0 -diiodoferrocene, respectively [11][12][13]. Some of the unsymmetrically substituted 1,1 0 -ferrocene diamides showed unique spectroscopic properties compared to others.…”

Synthesis of 1,1′-ferrocene bis(carboxypyrazole) compounds and displacement of the pyrazole ligands

“…Attempts to bind the new ferrocene compounds as bidentate ligands to a Mo(CO) 4 fragment did not produce the desired Mo(CO) 4 (N-N) complex. Instead, after a short reflux in CH 2 Cl 2 , both pyrazole rings were displaced and replaced with piperidine ligands from the molybdenum carbonyl reagent yielding the known compound, Fe(C 5 H 4 CONHC 5 H 10 ) 2 [17,18]. We attempted to determine whether the pyrazoles replaced the piperidines on the molybdenum metal center.…”

Synthesis of ferrocenoyl amino acid derivatives via homogeneous catalytic aminocarbonylation

“…According to our recent results, amino acid esters can be successfully used as nucleophiles in the aminocarbonylation of iodobenzene and alkenyl iodides [24]. Therefore, as the next step in our series of investigations concerning the carbonylation reactions of iodoferrocene derivatives [25][26][27][28], the aminocarbonylation of iodoferrocene in the presence of amino acid esters has been explored.…”