Facile synthesis of vinyl esters of aromatic carboxylic acids with participation of 2-chloro-4,6-dimethoxy-1,3,5-triazine

Abstract

In this work, the reaction of derivatives of benzoic acid containing substituents in the aromatic ring (1a-o) with 2-chloro-4,6dimethoxy-1,3,5-triazine (4) in the presence of N-methylmorpholine (6) has been synthesized active triazine esters of carboxylic acids (3a-o). These compounds obtained in the presence of potassium butylate (7) in reaction with vinyl acetate (2) have formed vinyl esters of corresponding aromatic carboxylic acids (5a-o). The electronic effect of the substitutor in the aromatic ring affects on carrying out of the reaction and the nature of obtained products. The structure of the synthesized vinyl esters of aromatic carboxylic acids was confirmed by FT-IR, 1H_NMR, 13C-NMR, and LC/MS spectral analysis, and some of their physical constants were determined.

Reaction of aromatic carboxylic acids with phenylacetylene with the participation of a zinc catalyst

“…Vinyl esters of carboxylic acids are active compounds and are used as intermediates in organic synthesis, polymerization reactions, hydrogenation and cross-cyclization. Currently, research and development work in chemistry, physics, technology and application of vinyl esters of carboxylic acids are rapidly developing [1].…”

Catalytic Reaction with Benzoic Acid Phenylacetylene in the Presence of Complex Catalysts

“…Various metal complex catalysts: Ru, Pd, Rh, Ir, Re, Au, and Ag affect the course of these reactions in different ways and have different selectivity. However, these metals are expensive and their complexes are relatively unstable [5][6][7]. The synthesis of vinyl esters using inexpensive and widely available metal catalysts is one of the urgent problems.…”