Facile synthesis of Zn0.5Ni0.5Fe2O4/carbon nanocomposite for hyperthermia and drug delivery applications

Rafizadeh, Mitra; Hassanzadeh-Tabrizi, S.A.

doi:10.1016/j.diamond.2022.108993

Cited by 9 publications

(2 citation statements)

References 83 publications

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“…[ 38 ] These antibacterial agents usually destroy the cell wall of bacteria or interfere with their metabolic functions which results in bacteria's death. [ 39 ] Antibiotics only help to combat one of the factors that prevent wounds from healing instead of truly accelerating the speed of tissue recovery. As pathogens are increasingly becoming immune to the reservoir of antibiotics and their ability to mutate is surpassing humans' intellect and initiative for creating new ones, many ‘forgotten’ remedies are once again gaining appeal.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of polyvinyl alcohol/dextran/Zataria wound dressing with superior antibacterial and antioxidant properties

Esfahani

Koupaei

Hassanzadeh-Tabrizi

2023

Vinyl Additive Technology

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The aim of the present research was to synthesize and characterize polyvinyl alcohol/dextran/Zataria essential oil hydrogel wound dressings. For this purpose, dressings were made with different concentrations of polymers (PVA and Dex) and ZMO by solvent casting method. By dissolving PVA and Dextran in de-ionized water, PVA-Dex gel was made. The polymeric solution was mixed with glycerol. The pH of PVA-DEX-Glycerol solution was adjusted to 3 and glutaraldehyde was used as a cross-linker. ZMO, as the antibacterial and antioxidant agent, was added to the samples in different percentages (2,5,10%). It was found that both Dex and ZMO significantly influenced the hydrophilicity, gel fraction, and water uptake capacity of hydrogel films. The results showed that by the addition of Dex to PVA, the contact angle decreased from 48.54 ± 0.95 to 45.90 ± 0.73 , whereas by the addition of ZMO, the contact angle increased to 71.1 ± 2.43. SEM investigations revealed that the fabricated films had a uniform structure and the surface roughness increased with the addition of ZMO. The results indicated an increased elongation of 11.5% with the incorporation of ZMO into the films. The antimicrobial evaluation of the produced films showed that the loading of 10% v/v ZMO could broaden the microbicidal activity of PVA/Dex/ZMO film. The investigations on the interactions between synthesized wound dressings and fibroblast cells showed that the addition of ZMO into hydrogel films improved cell viability. The findings showed that PVA/Dex/ZMO films could have considerable use as wound dressing.

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Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of polyvinyl alcohol/dextran/Zataria wound dressing with superior antibacterial and antioxidant properties

Esfahani

Koupaei

Hassanzadeh-Tabrizi

2023

Vinyl Additive Technology

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“…Because of its localized action and minimal side effects, magnetic hyperthermia (MH) is a potential tool for cancer treatment. It consists of an induced local heating by applying an external alternating magnetic field to magnetic nanomaterials delivered into a tumour tissue, leaving in turn the surrounding tissue intact [13,14] . A key parameter in MH is the amount of energy that is transformed into heat per mass of magnetic material, known as specific absorption rate (SAR).…”

Section: Introductionmentioning

confidence: 99%

Magnetic Hyperthermia Enhancement in Iron‐based Materials Driven by Carbon Support Interactions

Vizcaíno-Anaya

Herreros‐Lucas

Vila-Fungueiriño

et al. 2022

Chemistry A European J

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Magnetic hyperthermia (MH) shows great potential in clinical applications because of its very localized action and minimal side effects. Because of their high saturation magnetization values, reduced forms of iron are promising candidates for MH. However, they must be protected in order to overcome their toxicity and instability (i. e., oxidation) under biological conditions. In this work, a novel methodology for the protection of iron nanoparticles through confinement within graphitic carbon layers after thermal treatment of preformed nanoparticles supported on carbon is reported. We demonstrate that the size and composition of the nascent confined iron nanoparticles, as well as the thickness of their protective carbon layer can be controlled by selecting the nature of the carbon support. Our findings reveal that a higher nanoparticle–carbon interaction, mediated by the presence of oxygen‐containing groups, induces the formation of small and well‐protected α‐Fe‐based nanoparticles that exhibit promising results towards MH based on their enhanced specific absorption rate values.

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Synthesis of Cu0.5Zn0.5-xNixFe2O4 nanoparticles as heating agents for possible cancer treatment

Hassanzadeh-Tabrizi

2024

Arabian Journal of Chemistry

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Facile synthesis of Zn0.5Ni0.5Fe2O4/carbon nanocomposite for hyperthermia and drug delivery applications

Cited by 9 publications

References 83 publications

Synthesis and characterization of polyvinyl alcohol/dextran/Zataria wound dressing with superior antibacterial and antioxidant properties

Synthesis and characterization of polyvinyl alcohol/dextran/Zataria wound dressing with superior antibacterial and antioxidant properties

Magnetic Hyperthermia Enhancement in Iron‐based Materials Driven by Carbon Support Interactions

Synthesis of Cu0.5Zn0.5-xNixFe2O4 nanoparticles as heating agents for possible cancer treatment

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