Facile utility of felumin, a biological dye for the first fluorimetric determination of <scp>l</scp>-tetramisole drug through an “on–off fluorescence” strategy

Hamad, Ahmed Abdulhafez

doi:10.1039/d2ra08183k

RSC Adv.

2023

DOI: 10.1039/d2ra08183k

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Facile utility of felumin, a biological dye for the first fluorimetric determination of l-tetramisole drug through an “on–off fluorescence” strategy

Ahmed Abdulhafez Hamad

Abstract: The proposed fluorimetric system pathway and its on–off strategical response to the tested drug with the intrinsic fluorescence of the Felumin dye.

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2024

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Cited by 4 publications

References 55 publications

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Application of a white and green spectrofluorimetric approach for facile quantification of amlodipine, a hypotensive drug, in batch materials, dosage forms, and biological fluids; content homogeneity testing

Alqarni,

Haredy,

Abdelrahman

et al. 2024

Luminescence

Self Cite

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The suggested study adheres to a particular protocol to ensure that the process is environmentally friendly and sustainable. It is worth mentioning that several tools have been adopted as prospective measures of the method greenness. Fortunately, the established analytical method is identified as white by the white analytical chemistry (WAC) concept, which uses the red/ green/blue color scheme (RGB 12 tool) to combine ecological and functional factors for the first time in studying of the cited drug. Amlodipine (AMD), a cardiovascular treating agent, belongs to the dihydropyridine class of oral calcium channel‐blocking agents. This article presents a novel, simple, green, one‐pot‐processed, fast, and ultrasensitive fluorimetric approach for monitoring and assessment of AMD using molecular‐size‐dependent fluorescence augmentation of the light scattering‐driven signal of eosin, a biological stain at a wavelength of 415 nm. This enhancement was directly proportional to the size of the produced complex. The linearity range was from 30 to 900 ng mL−1, with corresponding sensitivity limits (detection and quantitation levels) of 9.2 and 28 ng mL−1, respectively. The planned approach was also successfully used to track AMD content in bulk, dosage forms, and bio‐fluids (human plasma and urine). The developed method's eco‐friendliness was established by different eco‐rating metric tools.

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Application of a white and green spectrofluorimetric approach for facile quantification of amlodipine, a hypotensive drug, in batch materials, dosage forms, and biological fluids; content homogeneity testing

Alqarni,

Haredy,

Abdelrahman

et al. 2024

Luminescence

Self Cite

View full text Add to dashboard Cite

show abstract

Facile Integration of Hanztsch's Switch-Off/On Modeled Fluorogenic Probe for Feasible Tagging and Tracking of the Midodrine Drug in Different Matrices; First Evaluation of the Method's Greenness, Whiteness, Blueness, Quantum Yield, and Tablets’ Content Homogeneity

Hamad,

Saleh,

Mahdi

et al. 2024

J Fluoresc

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Facile and Sustainable Electrostatic Integration of Eosin Y Dye for the Assay of the Atomoxetine Drug Through the Enhancement of the RRS Phenomenon

Al-Farhan,

Ibrahim,

Hassan

et al. 2024

J Fluoresc

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Facile utility of felumin, a biological dye for the first fluorimetric determination of l-tetramisole drug through an “on–off fluorescence” strategy

Abstract: The proposed fluorimetric system pathway and its on–off strategical response to the tested drug with the intrinsic fluorescence of the Felumin dye.

Cited by 4 publications

References 55 publications

Application of a white and green spectrofluorimetric approach for facile quantification of amlodipine, a hypotensive drug, in batch materials, dosage forms, and biological fluids; content homogeneity testing

Application of a white and green spectrofluorimetric approach for facile quantification of amlodipine, a hypotensive drug, in batch materials, dosage forms, and biological fluids; content homogeneity testing

Facile Integration of Hanztsch's Switch-Off/On Modeled Fluorogenic Probe for Feasible Tagging and Tracking of the Midodrine Drug in Different Matrices; First Evaluation of the Method's Greenness, Whiteness, Blueness, Quantum Yield, and Tablets’ Content Homogeneity

Facile and Sustainable Electrostatic Integration of Eosin Y Dye for the Assay of the Atomoxetine Drug Through the Enhancement of the RRS Phenomenon

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